摘要
目的:研究不同剂量左旋甲状腺素片治疗亚临床甲减孕妇患者的效果。方法:收治亚临床甲减孕妇72例,平分为常规剂量治疗对照组和小剂量治疗实验组,观察孕妇治疗前后的效果并比较。结果:两组治疗后的TT4、TT3水平均较治疗前高,且TSH水平降低,治疗前后差异有统计学意义(P<0.05);且实验组发生不良反应情况较对照组少(P<0.05)。实验组有孕妇实施阴道分娩27例,其余为剖宫产,无新生儿窒息、新生儿畸形以及胎死宫中现象;对照组有孕妇实施阴道分娩19例,患儿出现窒息2例。结论:低剂量左旋甲状腺素片治疗亚临床甲减孕妇不仅可以达到常规剂量药物的临床治疗效果,且能显著降低不良反应发生率,改善孕妇妊娠结局,降低新生儿并发症发生率,提高孕妇生活质量,有利于孕妇尽快恢复正常。
Objective:To study the effect of different doses of levothyroxine tablets in the treatment of subclinical hypothyroidism.Methods:72 patients with subclinical hypothyroidism were selected,they were divided into the two groups on average,the control group was treated with conventional dose,the experimental group received small dose treatment,the effect of pregnant women before and after treatment were compared.Results:The levels of TT4 and TT3 after treatment in the two groups were higher than those before treatment,and the level of TSH decreased.There was significant difference between the two groups before and after treatment(P<0.05).The adverse reaction of the experimental group was less than that of the control group(P<0.05),in the experimental group,27 pregnant women were given vaginal delivery and the rest were given cesarean section,no neonatal asphyxia,neonatal malformation and fetal death in uterus.In the control group,19 cases of vaginal delivery were carried out in pregnant women,with 2 cases of asphyxia in the children.Conclusion:Low dose of levothyroxine treatment for subclinical hypothyroidism can not only achieve the clinical therapeutic effect of routine dose of drugs,and can significantly reduce the incidence of adverse reactions,improve the pregnancy outcome of pregnant women,reduce the incidence of complications,improve the quality of life of pregnant women,which is good for pregnant women to return to normal as soon as possible.
出处
《中国社区医师》
2018年第6期87-88,共2页
Chinese Community Doctors
关键词
不同剂量
左旋甲状腺素片
亚临床甲减
临床效果
Different doses
Levothyroxine tablets
Subclinical hypothyroidism
Clinical effect
