摘要
目的评估SonoVue静脉应用于儿童的安全性及静脉超声造影（CEUS）在儿童腹部病变的诊断效能。方法53例患儿（8个月～18岁）经外周静脉注射66次造影剂，记录不良事件；行CEUS检查作出定性诊断，与病理或临床标准对照，评价其诊断效能。结果不良反应发生率为1．5％（1／66）。44例肝脏病变中CEUS的诊断敏感性100％，特异性95．65％，阳性预测值95．45％，阴性预测值100％，诊断准确性97．73％；余22例其他部位病变诊断符合率为100％。结论CEUS在儿童中应用是安全可靠的，值得在腹部病变患儿中推广。
Objective To investigate the security, applicability and diagnostic capacity of intravenous contrast-enhanced ultrasound （CEUS） in a pediatric population. Methods A total of 53 pediatric patients （8 months to 18 years old） received 66 intravenous applications of ultrasound contrast agent SonoVue. Side effects were documented. Histology, reference imaging or clinical diagnosis were compared with CEUS diagnostic results. Results Adverse effects occurred in 1/66 applications （1.5%）. For 44 focal liver lesions, the sensitivity was 100%, the specificity was 95.65%, the positive predictive value was 95.45% and the negative predictive value was 100%. The diagnostic accuracy was 97.73%. All 22 other lesions were diagnosed correctly. Conclusions It is safe and feasible to use intravenous CEUS in children. CEUS is worthy of promotion in pediatric patients with abdominal diseases.
出处
《中华超声影像学杂志》
CSCD
北大核心
2018年第1期36-42,共7页
Chinese Journal of Ultrasonography
基金
国家自然科学基金（81501480）
广东省自然科学基金（2015A0303130）
关键词
超声造影
儿童腹部病变
安全性
诊断效能
Contrast-enhanced ultrasonography
Pediatric abdominal disease
Security
Diagnostic efficiency
