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腹腔镜胃癌切除术和开腹手术在早期胃癌患者中的疗效对比观察及对生存期的影响研究 被引量:4

Study on the Effect of Laparoscopic Gastric Cancer Resection and Laparotomy in Early Gastric Cancer Patients
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摘要 目的:探讨腹腔镜胃癌切除术和开腹手术在早期胃癌患者中的临床效果及对生存期的影响。方法:取2015年5月—2017年5月医院收治的早期胃癌患者100例,随机数字法分为对照组(n=50)和观察组(n=50)。对照组采用开腹手术治疗,观察组采用腹腔镜胃癌切除术治疗,采用FACSAriaⅢ流式细胞仪测定2组治疗前、后免疫水平,比较2组临床疗效及对生存期的影响。结果:2组淋巴结清扫数、首次进食时间比较差异无统计学意义(P>0.05);观察组手术时间、术中出血量及术后肛门排气时间均短(少)于对照组(P<0.05);2组治疗前免疫指标水平差异无统计学意义(P>0.05),观察组手术后CD3^+、CD4^+、CD8^+及CD4^+/CD8^+均高于对照组(P<0.05);观察组术后1年、3年、5年生存期均高于对照组(P<0.05)。结论:将腹腔镜胃癌切除术用于早期胃癌患者中效果理想,有助于改善患者生存期及免疫水平,值得推广应用。 Objective: To explore the clinical effect of laparoscopic gastric cancer resection and open abdominal surgery in patients with early gastric cancer. Methods: In 100 cases of early gastric cancer patients admitted to hospital from May 2015 to May 2017,the random number method was divided into control group( n = 50) and observation group( n = 50). The control group treated with open operation,observation group treated by laparoscopic resection of gastric cancer,cells using FACSAriaⅢthe determination of two groups before treatment,after the immune level,compare the effects of two groups of clinical curative effect and animal survival. Results: There was no statistically significant difference between the two groups of lymph node dissection and the first feeding time( P > 0. 05). Observation group operation time,intraoperative blood loss and postoperative anal exhaust time were both short( less) in the control group( P < 0. 05). There was no statistically significant difference between the two groups before treatment( P > 0. 05). After surgery,the CD3+,CD4+,CD8+and CD4+/CD8+were all higher than the control group( P < 0. 05). The observation group was higher than the control group( P < 0. 05) after 1 year,3 years and 5 years after surgery. Conclusion: Laparoscopic gastric cancer resection for patients with early gastric cancer is ideal,which can improve the survival stage and immune level of patients,and it is worth promoting the application.
作者 韩元圣 丁丽
出处 《医学理论与实践》 2018年第1期3-5,共3页 The Journal of Medical Theory and Practice
关键词 胃癌切除术 腹腔镜 开腹手术 早期胃癌 生存期 Laparoscopic gastric cancer resection Open surgery Early gastric cancer Clinical effect The lifetime
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