摘要
目的分析不同结缔组织病合并甲状腺疾病的分布情况,探讨甲状腺疾病在结缔组织病发病机制中的作用。方法回顾性分析296例结缔组织病患者及同期健康体检者60例甲状腺疾病患病情况,并分别分析不同甲状腺疾病在系统性红斑狼疮(SLE)、干燥综合征(PSS)、类风湿关节炎、多发性肌炎及皮肌炎、系统性硬化症患者的分布情况,分析不同结缔组织病组与健康对照组的甲状腺抗体阳性率。结果结缔组织病患者合并甲状腺疾病明显高于健康对照组(P<0.05),SLE及PSS合并甲状腺疾病发生率较高,其中合并亚临床甲状腺功能减退症及甲状腺功能减退症发生率高,干燥综合征患者甲状腺抗体阳性率明显高于健康对照组(P<0.05)。结论结缔组织病与甲状腺疾病的发病机制相互作用,需监测不同结缔组织病患者的甲状腺功能情况。
Objective To analyze the distribution of different connective tissue diseases with thyroid diseases and to explore the correlation between thyroid disease and pathogenesis of connective tissue disease. Methods Retrospective analysis of 296 cases of connective tissue disease and the same period of physical examination of 60 cases of thyroid disease prevalence, and analyze different thyroid diseases in systemic lupus erythematosus, Sjogren＇s syndrome, rheumatoid arthritis, polymyositis and dermatomyositis and systemic sclerosis, and analyze the positive rate of thyroid antibody in different connective tissue disease group and healthy control group. Results The incidence of thyroid disease was significantly higher in patients with connective tissue disease than in healthy controls. The incidence of SLE and PSS complicated with thyroid disease was higher, and the incidence of subclinical hypothyroidism and hypothyroidism was higher, and in patients with Sjogren＇s syndrome the thyroid antibody positive rate was higher than the healthy control group. Conclusion Connective tissue disease is associated with the pathogenesis of thyroid disease, we need to monitor thyroid function in patients with different connective tissue diseases.
出处
《宁夏医学杂志》
CAS
2017年第12期1101-1102,共2页
Ningxia Medical Journal
