摘要
目的探讨RENAL、PADUA、C-index评分系统在T1期肾癌患者保留肾单位手术的临床应用有无差异,以及筛选出评分系统中与临床结果相关性较强的评分项目。方法回顾性分析收集符合纳入、排除标准的53例患者,应用非参数检验分析三种评分系统与临床结果之间的差异性,采用Spearman检验分析各评分子变量与临床结果之间的相关性。结果 RENAL、PADUA、C-index评分系统中的总体评价指标,低、中、高复杂度,在对T1期患者的应用中差异无统计学意义(P<0.05);在相关性方面,描述肿瘤与肾窦或与肾集合系统的位置关系的指标同手术时间、术中估计出血量具有较强的相关性(P<0.05),与热缺血时间、肌酐变化率、术后住院时间等无明显相关性(P>0.05)。结论临床实践中RENAL、PADUA、C-index评分系统对行NSS的T1期肾癌患者的评估均具有重要临床意义;在RENAL、PADUA、C-index评分系统的评分变量中,肿瘤外凸率、肿瘤与集合系统或肾窦的关系、C-index值这4个变量对临床评估T1期肾癌患者更具有指导意义。
Objective To investigate the clinical application of RENAL, PADUA, C - index score in patients with stage T1 renal cell carcinoma whom accepted nephron sparing surgery,and to select some parameter which is related to clinical outcomes. Methods 53 patients were evaluated according to the same criteria for this retrospective study. The nonparametfic test was used to analyze the difference between those score systems and the clinical results. Spearman correlation analyses were used to assess the correlation between the items of score systems and the clinical outcomes. Results There was no signifficant difference between score systems （ RENAL Score, PADUA Score,C -index Score） in the application of T1 RCC in patients（P 〈0.05）. The relationship between the tumor and the renal sinus or the location of the renal collecting system with the operation time, estimated blood loss have obvious correlations （ P 〈 O. 05 ）. There was no obvious correlation between the tumor and warm ischemia time, creatinine rate of change, postoperative hospital stay and so on （ P 〉 0.05 ）. Concluion This study suggests that each kind of RENAL score, PADUA score, C - index score for patients with the T1 RCC whom underwent the NSS have very important clinical significance. Those four parameter（ the tumor protruding rate, relationship be- tween tumor and collection system or renal sinus, C -index） of score system is helpful to evaluate patients with the T1 RCC .
出处
《宁夏医学杂志》
CAS
2017年第12期1072-1075,共4页
Ningxia Medical Journal
基金
国家自然科学基金资助项目(81460148)
宁夏自然科学基金资助项目(NZ16141)
宁夏自然科学基金项目(NZ17164)
