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An insight review of autophagy biology and neurodegenerative diseases:machinery,mechanisms and regulation 被引量:3

An insight review of autophagy biology and neurodegenerative diseases: machinery, mechanisms and regulation
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摘要 Autophagy is an intracellular catabolic system in which cytoplasmic proteins or organelles are translocated into lysosomes for degradation.Three different types of autophagy have been identified as macroautophagy,microautophagy,and chaperone-mediated autophagy(CMA). Autophagy is an intracellular catabolic system in which cytoplasmic proteins or organelles are translocated into lysosomes for degradation.Three different types of autophagy have been identified as macroautophagy,microautophagy,and chaperone-mediated autophagy(CMA).In macroautophagy,double-membraned phagophore develops autophagosome vesicles,which subsequently fuse with lysosomes to
出处 《Science China(Life Sciences)》 SCIE CAS CSCD 2017年第12期1457-1459,共3页 中国科学(生命科学英文版)
基金 supported by the National Natural Science Foundation of China(81430021,81771521) the Program for Liaoning Innovative Research Team in University(LT2015009) the Scientific Research Fund of Liaoning Provincial Education Department(L2015145) the Liaoning Science and Technology Project(2015225008)
关键词 An insight review of autophagy biology neurodegenerative diseases: machinery mechanisms and regulation CMA machinery mechanisms and regulation An insight review of autophagy biology and neurodegenerative diseases
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