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小剂量布比卡因复合芬太尼腰-硬联合麻醉在急诊剖宫产手术中的应用效果 被引量:4

Effect of combined spinal epidural anesthesia with low dose Bupivacaine combined with Fentanyl in emergency cesarean section
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摘要 目的探讨小剂量布比卡因复合芬太尼腰-硬联合麻醉在急诊剖宫产手术中的应用效果。方法选取2015年2月~2016年4月在我院急诊剖宫产手术产妇104例作为研究对象,采用随机数字表法将其分为单药组与联药组,每组52例。单药组给予布比卡因7.5 mg进行麻醉,联药组给予小剂量布比卡因5 mg+复合芬太尼20μg腰-硬联合麻醉。观察两组产妇手术麻醉结果、麻醉的优良率及不良反应发生情况。结果联药组麻醉起效时间、完全麻醉时间、肢觉恢复时间均短于单药组,差异有统计学意义(P<0.05);联药组痛觉恢复时间长于单药组,差异有统计学意义(P<0.05);联药组优良率高于单药组,差异有统计学意义(P<0.05);联药组不良反应发生率显著低于单药组(7.69%vs.25.00%),差异有统计学意义(P<0.05)。结论小剂量布比卡因复合芬太尼腰-硬联合麻醉在急诊剖宫产手术中起效快,镇痛效果较好,不良反应发生率较低,值得临床推广使用。 Objective To investigate the effect of combined spinal epidural anesthesia with low dose Bupivacaine com- bined with Fentanyl in emergency cesarean section.Methods From February 2015 to April 2016,104 cases of emergen- cy cesarean section in our hospital were selected as the research object,randomly divided into single drug group and combined treatment group,with 52 cases in each group.The single drug group was given Bupivacaine (7.5 mg) anesthesi- a,the combined drug group was given low dose Bupivacaine (5 mg)combined with Fentanyl (20 p,g) combined with spinal epidural anesthesia.The results of operation anesthesia,the excellent rate of anesthesia and adverse reactions were observed between the two groups.Results The combined treatment group anesthesia onset time,anesthesia time,com- pletely limb sensation recovery time were lower than those of the single drug group,the difference was statistically sig- nificant (P〈0.O5);The combined treatment group pain recovery time is higher than the single drug group,the difference was statistically significant (P〈0.05);Fine rate of the combined treatment group was higher than that of the single drug group,the difference was statistically significant (P〈0.05);The incidence of adverse reactions in the combined treatment group was significantly lower than that in the single drug group (7.69% vs. 25%),andthe difference was statistically sig- nificant (P〈0.05).Conclusion Low dose Bupivacaine combined with Fentanyl combined with lumbar epidural anesthesia is effective in emergency cesarean section and has good analgesic effect and low incidence of adverse reactions.It is worthy of clinical use.
作者 彭伟 况敏良
出处 《中国当代医药》 2017年第36期75-77,共3页 China Modern Medicine
关键词 布比卡因 芬太尼 联合麻醉 剖宫产 Bupivacaine Fentanyl Combined anesthesia Cesarean section
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