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帕瑞昔布钠用于神经外科术后镇痛的临床效果 被引量:6

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摘要 目的观察帕瑞昔布钠用于神经外科术后镇痛的临床效果和安全性。方法 40例择期行神经外科开颅手术的患者随机均分为P组和C组,分别于手术结束前30min静脉注射帕瑞昔布钠40mg和等容量的生理盐水。观察术后2、4、6、12、24h的VAS疼痛评分,术后2h检查凝血酶原时间(PT)和活化部分凝血活酶时间(APTT)。结果与C组相比,术后各时点P组VAS疼痛评分均降低(P<0.05)。术后2h两组PT和APTT差异无统计学意义(P>0.05)。结论神经外科手术术中静脉给予帕瑞昔布钠40mg可以安全、有效地缓解术后疼痛。
出处 《江苏医药》 CAS 2017年第24期1832-1833,共2页 Jiangsu Medical Journal
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