摘要
目的:探究阿托伐他汀钙片(立普妥)对糖尿病并发症的一级预防效果。方法:收治糖尿病患者80例,随机平分两组。对照组采用阿司匹林肠溶片治疗,观察组采用阿托伐他汀钙片(立普妥)治疗,比较两组治疗前后的糖脂代谢指标(TC、TG、LDL、HOMA-IRI、Hb A1c、FBG、FINS)、动脉粥样硬化发生率、心血管事件发生率。结果:治疗后,对照组各项糖脂代谢指标值均明显高于观察组,观察组的动脉粥样硬化发生率、心血管事件发生率均明显低于对照组,两组对比差异有统计学意义(P<0.05)。结论:采用阿托伐他汀钙片(立普妥)对糖尿病患者进行治疗,不仅能有效改善患者的糖脂代谢指数,从而改善患者临床症状,而且能有效降低患者并发动脉粥样硬化和心血管事件的概率,进而提高患者的生存质量。
Objective:To investigate the primary preventive effect of atorvastatin calcium(Lipitor)on diabetic complications.Methods:80 patients with diabetes mellitus were selected.They were randomly divided into the two groups on average.The control group was treated with aspirin enteric-coated tablets.The observation group was treated with atorvastatin calcium tablets(Lipitor).The blood glucose and lipid metabolism indexes(TC,TG,LDL,HOMA-IRI,Hb A1 c,FBG,FINS),the incidence of atherosclerosis and the incidence of cardiovascular events were compared between groups before and after treatment.Results:After treatment,the indexes of blood glucose and lipid metabolism in the control group were significantly higher than those in the observation group;the incidence of atherosclerosis and the incidence of cardiovascular events in the observation group were significantly lower than those in the control group;the differences between groups were statistically significant(P<0.05).Conclusion:The atorvastatin calcium tablets(Lipitor)for the treatment of diabetic patients can effectively improve the lipid metabolism index of patients,so as to improve the clinical symptoms of patients,and it can effectively reduce the risk of patients with atherosclerosis and cardiovascular events,and improve the quality of life of patients.
出处
《中国社区医师》
2018年第1期80-81,共2页
Chinese Community Doctors
关键词
阿托法他汀钙片(立普妥)
糖尿病
并发症
一级预防
Atorvastatin calcium tablets(Lipitor)
Diabetes mellitus
Complications
Primary prevention
