摘要
目的探讨针刺结合中药人工周期疗法对体外受精卵巢反应低下患者的临床疗效。方法选取120例符合卵巢反应低下的患者随机分为观察组、空白组、中药组、针刺组,在进入体外受精治疗程序前3个月进行预处理,对观察组行针刺结合中药人工周期疗法治疗,对中药组行中药人工周期疗法治疗,对针刺组行针刺治疗,空白组不做任何治疗。检测两组治疗后的FSH水平、在IVF-ET中的Gn用量、取卵数、胚胎数、临床妊娠率。结果观察组Gn用量、获卵数及胚胎数高于空白对照组、中药组、针刺组,有统计学差异(p<0.05)。中药组、针刺组Gn用量、获卵数及胚胎数高于空白对照组,有统计学差异(p<0.05)。中药组、针刺组Gn用量、获卵数及胚胎数比较无统计学差异(p>0.05)。观察组妊娠率35.7%(10/28),空白组妊娠率23.3%(7/30),中药组妊娠率26.7%(8/30),针刺组妊娠率27.5%(8/29),经t检验方法统计分析,观察组妊娠率高于其余3组,比较有统计学差异(p<0.05),针刺组妊娠率高于空白组、中药组,比较有统计学差异(p<0.05)中药组妊娠率高于空白组,较有统计学差异(p<0.05)。结论针刺结合中药人工周期疗法对卵巢低反应患者的内分泌水平的调节具有良性作用,针刺结合中药人工周期疗法对卵巢反应低下患者进行促排卵前预处理,对增加后续IVF-ET术中可移植胚胎数及临床妊娠率,对提高卵巢反应低下患者的妊娠率提供了新的治疗方案。
Objective To explore the clinical effect of acupuncture combined with Traditional Chinese medicine artificial cycle therapy on the patients with infertile ovary. Method Choose 120 cases accord with low ovarian response of patients were randomly divided into observation group and the blank group, Chinese medicine group,acupuncture group, before In vitro fertilization（ivf） 3 months, the observation group accepts the treatment of acupuncture combined with traditional Chinese medicine artificial cycle therapy, the Chinese medicine group accepts the treatment of Traditional Chinese medicine artificial cycle therapy, acupuncture group accept acupuncture therapy. The blank group does not do any treatment. Detect the clinical pregnancy rate, the number of embryos, the FSH level, Gn dosage in IVF-ET after treatment. Results The observed group, Gn dosage, the number of eggs obtained and the number of embryos were higher than that of the blank control group, the Chinese medicine group, the acupuncture group, and there were statistical differences（p0.05）. There was a statistical difference（p0.05） in Chinese medicine group, acupuncture group, Gn dosage, ovulation number and embryo number above the blank control group. Chinese medicine group, acupuncture group Gn dosage, attains the number of eggs and embryos is no statistical difference（p0.05） between Chinese medicine group and acupuncture group, the observation group pregnancy rate 35.7%（10/28）, blank group pregnancy rate 23.3%（7/30）, Chinese medicine group pregnancy rate 26.7%（8/30）, pregnancy rate 27.5%（8/29）, acupuncture group by t test method, statistical analysis, observation group pregnancy rate is higher than the rest of the three groups,and is statistically significant（p0.05）. In acupuncture group the pregnancy rate is higher than that of blank group, Chinese medicine group, with statistical difference（p0.05） traditional Chinese medicine（TCM）pregnancy rate is higher than the blank group, and is statistically significant（p
出处
《佛山科学技术学院学报（自然科学版）》
CAS
2017年第6期57-61,共5页
Journal of Foshan University(Natural Science Edition)
基金
广东省中医药局项目(20142138)
关键词
体外受精
卵巢反应低下
针刺结合中药人工周期疗法
In vitro fertilization
Low ovarian reaction
acupuncture combined with Traditional Chinese medicineartificial cycle therapy
