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microRNA与胃癌相关信号通路调控的研究进展 被引量:7

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摘要 胃癌是全球较常见的恶性肿瘤之一,其预后较差。在多数胃癌患者中,一些信号通路中的癌基因处于过度激活状态,而抑癌基因则处于失活状态。微RNA(microRNA,miRNA)是一种短链非编码RNA,在肿瘤组织中异常表达,具有促癌或抑癌作用。miRNA通过调控癌基因或抑癌基因信号通路参与肿瘤细胞的增殖、凋亡、周期调控、血管生成及侵袭转移。该文就miRNA调控胃癌相关信号通路的研究进展作一综述。
出处 《国际消化病杂志》 CAS 2017年第6期361-365,共5页 International Journal of Digestive Diseases
基金 国家自然科学基金面上项目(81573747) 香江学者计划(XJ2015033)
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