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手术治疗非小细胞肺癌预后多因素分析 被引量:9

Multivariate Prognostic Analysis of Surgical Treatment for Non-small Cell Lung Cancer
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摘要 目的研究多种因素对非小细胞肺癌患者预后的影响。方法回顾性分析行手术治疗的非小细胞肺癌患者150例临床资料。结果术后4年经5次调查,生存率分别为86%、76%、70%、66%、62%。单因素分析表明:性别、年龄、手术后的Tumor Node Metastasis(TNM)分期、肿瘤大小、淋巴结是否发生转移、手术治疗方式、手术前血红蛋白和白蛋白等因素可以影响预后。多因素分析表明:肿瘤大小、TNM分期、淋巴结是否发生转移以及转移程度等为独立性预后因素。结论进行手术治疗非小细胞肺癌治疗患者肿瘤细胞的大小、手术后的TNM分期、淋巴结是否发生转移以及转移的程度、手术治疗的方式等独立因素可以影响预后;影响非小细胞肺癌患者预后保护因素有手术前的血红蛋白和性别。 Objective To study the effects of various factors on the prognosis of patients with non-small cell lung canc- er. Methods Clinical data of 150 patients with non-small cell lung cancer who underwent surgical treatment were retrospectively analyzed. Results After 4 years of operation, the survival rates were 86% ,76% ,70% ,66% and 62% after 5 investigations. Sin- gle factor analysis showed that gender, age, postoperative tumor node metastasis (TNM) staging, tumor size,lymph node metastasis, whether the factors of surgical treatment, preoperative hemoglobin and albumin can affect the prognosis. Multivariate analysis showed that tumor size, TNM staging,lymph node metastasis and metastasis were independent prognostic factors. Conclusion Independent factors for patients with tumor surgery in the treatment of non-small cell lung cancer after surgery are size,TNM stage, lymph node metastasis and metastasis, surgical treatment methods can affect the prognosis of patients;protective factors are small cell lung cancer with preoperative hemoglobin and gender.
出处 《实用癌症杂志》 2018年第1期75-78,共4页 The Practical Journal of Cancer
关键词 非小细胞肺癌 手术治疗 TNM分期 预后 Non-small cell lung cancer Surgical treatment TNM staging Prognosis
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