摘要
出血性休克与脑病综合征（hemorrhagic shock and encephalopathy syndrome，HSES）是Levin于1983年首次提出的一种见于婴儿期的严重疾病。HSES的主要临床特点是前驱感染症状发热、腹泻后，随之出现抽搐、意识障碍、出血倾向、休克及多器官损害。病理表现为多脏器点状出血、坏死或炎性改变。其病因不明，预后差，尽管进行积极的治疗，但病死率极高，幸存者多遗留神经系统后遗症。目前，本病尚无特效治疗方法，主要以早期对症、支持治疗为主。
Hemorrhagic shock and encephalopathy syndrome （HSES）is a devastating disease in infants which was first proposed by Levin in 1983. The main clinical manifestations of HSES are associated with acute onset of high fever, diarrhea, rapidly followed by convulsions, unconsciousness, bleeding tendency, shock and multiorgan dysfunction. The pathological manifestations include punetate bleeding, necrosis or inflammatory changes in multiple organs. The etiology of this syndrome is unknown, and the prognosis is poor. Despite intensive treatment, the fatality rate is still high and the survival is often associated with severe neurological sequelae. At present, there is no effective treatment for this disease, and mainly early symptomatic and supportive treatment can be obtained.
出处
《中华实用儿科临床杂志》
CSCD
北大核心
2017年第24期1845-1848,共4页
Chinese Journal of Applied Clinical Pediatrics
关键词
出血性休克与脑病综合征
研究进展
儿童
Hemorrhagic shock and encephalopathy syndrome
Research progress
Child
