摘要
目的探讨卡前列素氨丁三醇治疗子宫收缩乏力性产后出血的临床止血效果及不良反应。方法选取2015年1月~2017年1月我院住院的子宫收缩乏力产后出血产妇64例作为研究对象,随机分为观察组和对照组各32例。对照组予米索前列醇直肠给药0.4mg+缩宫素20U静脉滴注,同时按摩子宫。观察组予以卡前列素氨丁三醇0.25 mg宫体注射,效果不佳时,每次可间隔15 min,总量不超过2 mg。对比两组患者的止血效果及不良反应情况。结果观察组治疗后的总有效率为93.75%,显著高于对照组,两组临床疗效对比差异具有统计学意义(均P<0.05),观察组患者产后2h、24 h的出血量显著少于对照组(P<0.05),且观察组患者治疗后的不良反应发生率显著低于对照组(P<0.05)。结论卡前列素氨丁三醇用于子宫收缩乏力性产后出血的临床止血效果好,不良反应少,值得临床广泛推广和应用。
Objective To investigate the clinical hemostatic effect and adverse reactions of carboprost trometamol in the treatment of postpartum hemorrhage from uterine atony. Methods 64 puerperas with postpartum hemorrhage from uterine atony in our hospital from January 2015 to January 2017 were selected as study subjects and randomLy divided into observation group （n=32） and control group （n=32）. The control group was treated with misoprostol 0.4 mg rectally and oxytocin 20 U by intravenously guttae, while was given the uterus massage. The observation group was given cardoprost trometamol 0.25 mg by intrauterine injection.When the effect was not good, the drug could be injected at 15 rain intervals, and the total did not exceed 2 rag. The hemostatic effects and adverse reactions were compared between the two groups. Results The total effective rate of the observation group after treatment was 93.75%, which was significantly higher than that of the control group. There was significant difference between the two groups in the clinical curative effect（all P〈0.05）. The postpartum hemorrhage（2 h,24 h） in the observation group after treatment was significantly less than that in the control group（P〈0.05）. The incidence of adverse reactions in the observation group was significantly lower than that in the control group（P〈0.05）. Conclusion The carboprost trometamol has good clinical hemostatic effect in the treatment of postpartum hemorrhage due to uterine atony deficiency and few the adverse reactions, which is worthy of widely clinical application.
出处
《中国现代医生》
2017年第35期50-52,共3页
China Modern Doctor
