摘要
目的:探讨MR体素内不相干运动扩散加权成像对肺部良、恶性占位的鉴别诊断价值。方法:对40例肺部占位患者(经病理证实良性者14例,恶性者26例)进行回顾性研究,所有患者行胸部常规序列(T_1WI,T_2WI)及IVIM-DWI检查。并用后处理软件进行后处理,得到良、恶性病变的ADC值、D(扩散系数)、D*(灌注相关扩散系数)、f(灌注分数)值,采用独立样本t检验比较良、恶性占位各参数的差异。结果:肺良性占位ADC值:(1242.22±261.16)×10^(-6) mm^2/s;D值:(1178.0±462.6)×10^(-6) mm^2/s;f值:(0.45192±0.17260);肺恶性占位ADC值:(820.62±238.69)×10^(-6) mm^2/s,D值:(854.6±302.6)×10^(-6) mm2/s,f值:(0.28397±0.14539);两组间差异均有统计学意义(P<0.05);肺良性占位D*值:(26860±40505)×10^(-6)mm^2/s,肺恶性占位D*值:(22810±37930)×10^(-6) mm^2/s,两组间差异无统计学意义(P>0.05)。结论:在肺部良性病变与恶性肿瘤的鉴别诊断中,IVIM、DWI的参数ADC值、D值及f值有一定临床意义。
Objective:To evaluate the role of intravoxel incoherent motion of diffusion weighted imaging in the differential diagnosis of lung lesions.Methods:Forty patients with lung masses(14 benign,26 malignant were confirmed by pathology)were undergone enhanced CT scanning were included in this retrospective study.All patients were undergone conventional MRI and IVIM-DWI examination of the chest.The MTKL post-processing software was used to calculate the value of ADC,D,D*and f of the benign and malignant lesions,which were recorded and compared.T test was used to compare the difference of the values of different parameters.Results:Benign lesions and lung cancer ADC values were(1242.22±261.16)×10^(-6) mm^2/s,(820.62±238.69)×10^(-6) mm^2/s respectively,D values were(1178.0±462.6)×10^(-6) mm^2/s,(854.6±302.6)×10^(-6) mm^2/s,and f values were(0.45192±0.17260),(0.28397±0.14539),and the difference was statistically significant(P<0.05);D*values were(26860±40505)×10^(-6) mm^2/s for the benign lesions and(22810±37930)×10^(-6) mm^2/s for the malignant respectively,the difference was not statistically significant(P>0.05).Conclusions:The intravoxel incoherent motion based on diffusion weighted imaging is useful for distinguishing between the benign and malignant lung lesions.
出处
《陕西医学杂志》
CAS
2018年第1期11-13,16,共4页
Shaanxi Medical Journal
基金
陕西省咸阳市科学技术局科研项目(2016K02-97)
关键词
肿瘤/病理学
肿瘤/诊断
磁共振成像
@磁共振扩散加权成像
@体素内不相干运动
Neoplasms/pathology
Neoplasms/diagnosis
Magnetic resonance imaging
Pulmonary mass
@Magnetic resonance diffusion weighted imaging
@Intravoxel incoherent motion
