摘要
本研究应用呼吸阻力(Rrs)和FEV_1,对支气管哮喘缓解期(A组)、发作期(B组)、哮喘合并肺气肿(C组)患者的气道阻塞可逆性进行检测。结果B、C组的Rrs改善率和改善量均大于A组,C组的改善量又大于B组;B、C组的FEV_1改善率和改善量亦大于A组,B、C组之间无显著差别。Rrs与FEV_1的改善率和改善量有明显的相关。根据二者的相关方程,得到相当于FEV_1改善10%、200mlRrs改善率22.21%和改善量1.39cmH_2O/L·See^(-1),为临床应用呼吸阻力进行哮喘气道阻塞的可逆性判定和药物疗效的观察,提供可循的依据。
The reversibility of airway obstruction was examined with respiratoryresistance (Rrs) and FEV_1 in patients with bronchial asthma, who were inthe remission condition (group A), acute exacerbation (group B) and accom-panied by emphysema (group C), The results indicated that (1) the improvingrate and quantity of Rrs in groups B and C were greater than those in groupA and the improving quantity in group C was greater than that in group B:(2) the FEV_1 improving rate and puantity in groups B and C were alsogreater than those in group A and there was no significant difference betweengroups B and C; (3) the improving rate and quantity of Rrs was closely correlatedwith those of FEV_(1.0). From the correlation equation obtained, Rrs improvingrate (22.21%) and improving quantity (1.39 om H_2O) ,were derived fromthe FEV_1 improving rate (10%) and improving quantity (200 ml). The presentstudy provides a useful index to assess the reversibility of airway obstructionand the effectiveness of drug therapy in patients with bronchial asthma.
出处
《中国医科大学学报》
CAS
CSCD
1991年第5期372-374,共3页
Journal of China Medical University
关键词
哮喘
气道阻塞
呼吸阻力
bronchial asthma
airway obstruction
respiratory resistance
