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儿童多发性抽动症复发高危因素logistic回归分析 被引量:13

Logistic Regression Analysis of Risk Factors of Recurrent Disease in Children with Tourette's Syndrome
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摘要 目的 :探讨儿童多发性抽动症复发的高危因素,为进一步防治儿童多发性抽动症提供一定的研究思路。方法 :收集2015年10月—2016年4月辽宁中医药大学门诊及住院部多发性抽动症患者70例作为研究对象,总随访时间为6个月。采用统一制定的调查问卷,从性别、年龄、病程、母亲孕龄、喂养方式、父母文化程度、家庭关系、教养方式、患儿性格特点、父母性格特点、饮食习惯、生理性黄疸史、病理性黄疸史、分娩方式等方面进行研究。应用单因素及多因素Logistic回归分析方法分析儿童多发性抽动症的复发因素。结果 :70例患儿中最终分析62例,失访8例,失访率12.9%。通过单因素分析的结果中初步筛选影响因素,生产喂养方式、情绪、新生儿黄疸、饮食不合理、家庭因素差异有统计学意义(P<0.05)。再将以上因素引入多因素Logistic回归分析得出:情绪紧张、剖腹产、新生儿黄疸、饮食不合理差异有统计学意义(P<0.05)。结论 :情绪紧张、剖腹产、新生儿黄疸、饮食不合理是儿童多发性抽动症的独立危险因素,能够容易引起儿童多发性抽动症复发。 Objective :To explore the risk factors of relapse in children with tourette's syndrome,for further prevention and treatment of children with multiple tics to provide some research ideas.Methods :A total of 70 patients with tourette's syndrome in Liaoning university of traditional Chinese medicine from October 2015 to April 2016 were enrolled in this study.The total follow-up time was about 6 months.Using the unified questionnaire,gender,age,course of disease,from the mother's gestational age,feeding patterns,parents' educational level,family relationship,parenting style,children personality,parents' personality traits,eating habits,physiological jaundice history,pathological jaundice history,study of labor mode etc.Single factor and multi factor Logistic regression analysis of recurrence factors in children with tourette's syndrome.Results :In 70 cases,the final analysis was performed in 62 cases,and the follow-up rate was 12.9%.The rate of missed diagnosis was about 8.Through the single factor analysis of the results of the initial screening of factors affecting the production of feeding patterns,emotions,neonatal jaundice,diet unreasonable,family factors were statistically significant(P〈0.05).Then the above factors were introduced into multi factor Logistic regression analysis.The results showed that there were significant differences in emotional stress,caesarean birth,neonatal jaundice,and unreasonable diet(P〈0.05).Conclusion :Emotional tension,cesarean section,neonatal jaundice,unreasonable diet are independent risk factors of tourette's syndrome,can easily lead to recurrence of tourette's syndrome in children.
作者 曹晓芳
出处 《辽宁中医药大学学报》 CAS 2017年第12期174-176,共3页 Journal of Liaoning University of Traditional Chinese Medicine
基金 沈阳市科技专项基金项目(F15-139-9-40)
关键词 多发性抽动症 儿童 高危因素 tourette's syndrome children risk factors
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