摘要
目的探讨遵义医学院附属医院内镜中心近10年来检出的大肠癌发病情况、临床表现、内镜及病理特点,进一步阐明本地区大肠癌流行病学特征和临床特点。方法以我院2007—2016年来所有接受结肠镜检查的患者为研究对象,对大肠癌患病率、大肠癌患者性别、年龄、肿瘤部位、病理类型等进行回顾性分析与总结。结果 10年间共行大肠镜检查51 732例,检出大肠癌2 127例,占受检总数4.11%。2 127例大肠癌中,男1 267例、女860例。发病高峰年龄段在50~79岁之间,尤其是60~69岁之间;结肠癌714例、直肠癌1 413例;病理分类以腺癌为主,尤其以高分化腺癌为主,与性别无明显差异,但印戒细胞癌女性明显多于男性,差异有统计学意义(P<0.05)。结论贵州省北部地区的大肠癌发病近年来呈逐渐上升趋势,男性发病明显多于女性,直肠癌是结肠癌发病的两倍左右,病理类型上女性大肠癌患者要注意印戒细胞癌的发生。因此,预防上重点对高危人群进行大肠癌普查、直肠指诊和结肠镜检查,可以有效地提高大肠癌的早诊早治率。
Objective To investigate the morbidity, clinical manifestations, endoscopic and pathological characteristics of colorectal cancer in the Endoscopic Center of The Affiliated Hospital of Zunyi Medical College from 2007 to 2016, and fnrther expound the epidemiological and clinical characteristics of colorectal cancer in local district. Methods All patients treated with colonoscopy in The Affiliated Hospiatal of Zunyi Medical College in the past 10 years were involved. We analyzed and summarized the morbidity of colorectal cancer and colorectal cancer patients＇ gender and age, tumor location and pathological type retrospectively. Results We examined 51732 cases by colonoscopy in the past 10 years, among which 2127（4.11%） cases were colorectal cancer（1267 males and 860 females; 714 cases of colon cancer and 1413 cases of rectal cancer）. The peak age of onset was 50-79 years old, especially 60-69 years old. Adenocarcinoma was the mainly pathological classification, especially well-differentiated adenocarcinoma, and they were not significantly different in gender. But the number of female patients with signet-ring cell carcinoma were more than male patients （P〈0.05）. Conclusion In recent years, the incidence of colorectal cancer has been increasing in the north of Guizhou Province. The number of male patients is more than females. The incidence of rectal cancer is about two times as much as colon cancer. The female patients with colorectal cancer must be paid attention to the occurrence of signet ring-cell carcinoma in pathological classification. We must strengthen the survey on colorectal cancer, rectal digital examination and colonoscopy in high-risk people, which can improve early diagnosis and treatment of colorectal cancer.
出处
《肿瘤防治研究》
CAS
CSCD
北大核心
2017年第12期836-839,共4页
Cancer Research on Prevention and Treatment
关键词
大肠癌
肠镜
病理
诊断
Colorectal cancer
Colonoscopy
Pathology
Diagnosis
