摘要
目的分析肥城矿业中心医院2016年临床用药引发的不良反应,为临床正确使用药物提供依据。方法回顾性分析肥城矿业中心医院2016年1月1日-12月31日收集上报的482例药物不良反应(adverse drug reaction,ADR)数据,根据患者年龄、药物剂型、类别、ADR累及系统及主要临床表现进行统计。结果 482例ADR报告中,男性310例(64.32%),女性172例(35.68%)。>60岁255例(52.90%);以静脉滴注占比最高(393例,81.54%);主要损害皮肤和附件(120例,24.90%);ADR涉及的药物以心血管药物居首(131例,27.18%),其次为抗肿瘤药物(114例,23.65%)。结论本院ADR主要集中发生在老年人中,心血管药物与抗肿瘤药物更易引起ADR发生,临床应合理用药以减少或避免ADR发生。
Objective To summarize the adverse reactions in our hospital in 2016 and provide references for clinical rational use of drugs. Methods A total of 482 ADR cases collected in our hospital from January to December in 2016 were analyzed statistically in respect of patients’ age, dosage form, drug categories and clinical manifestation. Results Of the 482 ADR cases, 310 （64.32%） were male and 172 （35.68%） were female. Patients over 60 years accounted for the largest proportion （255 cases, 52.90%）. ADRs caused by intravenous administration were most prevalent, accounting for 81.54%. Skin and accessories system were commonly involved （120 cases, 24.90%）. Cardiovascular drugs headed the list of ADR related drugs （131 cases, 27.18%）, followed by anti-tumor drugs （114 cases, 23.65%）. Conclusion Greater attention should be paid to drug safety in elderly patients. Rational use of cardiovascular and anti-tumor drugs should be strengthened to reduce and avoid ADR.
出处
《解放军医学院学报》
CAS
2017年第12期1151-1154,共4页
Academic Journal of Chinese PLA Medical School
关键词
药物不良反应
药物监测
临床用药
adverse drug reaction
drug monitoring
clinical medication
