摘要
为了解性病门诊中就诊妇女阴道感染的检出率、临床表现、疗效及性传播性,在5家性病门诊选择具有阴道分泌物异常主诉、初诊、年龄在16岁或以上、既往2周内未用过抗生素的妇女作为研究对象。取泌尿生殖道标本,应用常规实验室检查方法,检测淋球菌、沙眼衣原体、阴道毛滴虫、白念珠菌及细菌性阴道病。用常规治疗方法观察治疗效果。结果在649例女性中,共检出淋病123例(19.0%),衣原体感染130例(20.0%),滴虫感染63例(9.7%),念珠菌病143例(22.0%),细菌性阴道病109例(16.8%),另有205例未检出上述病原体。单一病原体感染为325例,一种以上病原体复合感染119例。3种阴道感染中,具有典型阴道分泌物性状者为36.7%～64.3%,对常规治疗的临床治愈率为46.3%～72.9%。滴虫病(OR=6.67,P<0.05)和细菌性阴道病(OR=2.23,P<0.05)分别与未坚持使用安全套有关。但是如果剔除合并宫颈感染的病例,则无这种相关性。表明在性病门诊就诊妇女中,阴道感染比宫颈感染更多见,复合感染也常见。阴道感染的临床表现不典型,对常规推荐治疗的疗效不理想,需要密切随访。阴道感染与性传播的危险因素无显著相关性。
To investigate the prevalence,clinical manifestations,therapeutic effects and sexual transmission of vaginal infec-tions among women attending sexually transmitted diseases(STD)clinics,women with vaginal abnormal discharge,age of16or older,and not taking any antibiotic in previous two weeks,who visited one of five STD clinics for the first time,were re-cruited.Five pathogens,Neisseria gonorrhoeae,Chlamydia trachomatis,Trichomonas vaginalis,Candida albicans and bacterial vaginosis,were examined by routine laboratory procedures.The therapeutic effectiveness upon recommended regimens were evaluated.One hundred and twenty-three(19.0%)of gonorrhea,130(20.0%)of chlamydial infection,63(9.7%)of tri-chomonasis,143(22.0%)of candidiasis,and109(16.8%)of bacterial vaginosis were found in649women.Two hundred and five cases had negative results.There were325cases infected with single pathogen and119with more than one pathogens.Among cases with3vaginal infections,36.7%～64.3%had typical presentations of vaginal discharge,and46.3%～72.9%achieved clinical cure.There were significant correlation between no consistent condom use with both trichomonasis and bac-terial vaginosis,however,those correlation disappeared after the patients coinfected with cervical infection were excluded.It is indicated that vaginal infections are more often to be detected than cervical infections in women presenting with vaginal discharge in STD clinics.Multiple infections are common.Those women are more likely to have atypical vaginal discharge and unsatisfactory response to routine therapeutic regimens.Careful following-up is necessary.No significant relationship is observed between vaginal infections and risk factors for sexual transmission.
出处
《临床皮肤科杂志》
CAS
CSCD
北大核心
2002年第9期548-550,共3页
Journal of Clinical Dermatology
