摘要
目的探讨胸外科手术中单肺通气对患者心功能及血流动力学的影响。方法选择美国麻醉医师协会(American of society anesthesiologists,ASA)分级Ⅰ~Ⅱ级,择期全身麻醉下侧卧位行双腔气管插管手术患者101例。应用FloTrac/Vigileo系统监测患者各项血流动力学参数。记录时间点分别为患者入室后(T_0)、插管后仰卧位双肺5 min(T_1)、侧卧位双肺5min(T_2)、侧卧位单肺5 min(T_3)、侧卧位单肺10 min(T_4)、侧卧位单肺30 min(T_5)、侧卧位单肺60 min(T_6)、鼓肺后(T_7)、平卧位双肺5 min(T_8)。结果 T0时MAP、HR高于T_2(P<0.05);T_1时SVR高于T6(P<0.05);T_1、T_2时MAP、HR、CO、CI低于T_3(P<0.05);T_3时MAP高于T_4,HR低于T_4(P<0.05);T_5时SpO_2最低(P<0.05);T_6时HR高于T7,MAP、SV低于T7(P<0.05),余比较无统计学差异。结论单肺通气后,患者出现短暂的血流动力学不稳,与双肺通气时比较MAP、HR、CO、CI增高,SpO_2、SVR减低,但随着单肺通气时间延长,各指标逐渐达到平稳状态。
Objective To evaluate the effect of one lung ventilation （ OLV ） on patient＇ s cardiac function and hemodynamic status during thoracic surgery by FloTrac/Vigileo system. Methods A total of 101 class Ⅰ - Ⅱ adult patients by American Society of Anesthesiologists （ASA） who had undergone the double lumen endotracheal intubation in the lateral position during thoracic surgery were enrolled in this study. Each hemodynamic parameter was recorded by FloTrac/Vigileo system at different time points that includ- ed the time before anesthesia induction（ TO ）, 5 rain into intubation in the supine position by two lung ventilation （T1 ） , 5 rain after the lateral position by two lung ventilation（ T2 ） ,5 min after OLV （T3 ） , 10 min after OLV（ T4 ） , 30 min after OLV（ T5 ） , 60 min after OLV （ W6 ） , after lung inflation （ T7 ）, and 5 min after the supine position by two lung ventilation （ T8 ）. Results MAP and HR were higher at TO than at T2 （P 〈 0.05 ）. SVR was higher at T1 than at T6 （P 〈 0.05 ）. MAP, HR, CO and CI were lower at Tl ,T3 than at T4 （ P 〈 0.05 ）. MAP was higher at T2 than at T4, and HR was lower at T3 than at T4 （ P 〈 0.05 ）. SpO2 was the lowest at T5 （ P 〈 0.05 ）. HR was higher at T6 than at T7 , while MAP and SV were lower at T6 than at T7 （P 〈 0.05）. Conclusions After one lung ven- tilation, patients can experience transient hemodynamic instability, tend to decrease compared with double lung ventilation. However, come stable. for MAP, HR, CO and CI tend to increase while SpO2 and SVR as the one lung ventilation continues, the indicators gradually become stable.
出处
《武警医学》
CAS
2017年第10期1005-1007,1011,共4页
Medical Journal of the Chinese People's Armed Police Force
