摘要
肿瘤干细胞(cancer stem cell,CSC)是一类具有自我更新、高致瘤性,分化潜能、高度耐药等特征的恶性肿瘤细胞群.CSC不仅保留了正常干细胞的性质,并且独具自身特点,研究CSC,为肿瘤的靶向治疗开辟新途径.本文将对CSC的定义、表面标志、检测方法与分离方法的研究进展进行综述.
Cancer stem cells are a class of malignant cancer cells characterized by self-renewal, hightumorigenicity, differentiation potential, and drug resistance. They not only retain the characteristics of normal stem cells, but also possess their unique features. The study of cancer stem cells can help us develop new strategies for targeted therapy of cancer. In this paper, we will discuss the definition of cancer stem cells, their surface markers,detection methods, and separation methods.
出处
《世界华人消化杂志》
CAS
2017年第31期2776-2781,共6页
World Chinese Journal of Digestology
