摘要
目的比较腹腔镜与开腹手术治疗结肠癌的临床疗效和术后生活质量况。方法分析中山大学附属第三医院粤东医院2014年5月至2016年3月收治的60例结肠癌患者的临床资料,依据手术方式分为腹腔镜组30例和开腹组30例。观察两组结肠癌患者临床疗效、预后以及术前、术后的生活质量评分情况。结果开腹组和腹腔镜组淋巴结清扫数目[(25.1±5.0)cm和(24.8±5.6)cm]、切除标本长度[(17.8±5.4)cm和(16.8±5.3)cm]、肿瘤远端长度[(3.1±1.5)cm和(2.8±1.4)cm]差异均无统计学意义(P>0.05),结肠癌患者术前疼痛[(66.8±10.8)分和(67.5±10.4)分]、饮食受限[(66.2±10.1)分和(67.1±10.3)]分、焦虑[(66.2±10.1)分和(67.6±10.3)]分、排便功能评分[(66.1±10.2)分和(67.1±10.3)分]差异均无统计学意义(P>0.05);腹腔镜组结肠癌患者局部复发率(6.7%)、远处转移率(6.7%)均低于开腹组的26.7%、26.7%,术后开腹组和腹腔镜组疼痛[(76.8±10.1)分和(87.9±10.5)分]、饮食受限[(76.6±10.2)分和(87.5±10.4)分]、焦虑[(76.3±10.5)分和(87.9±10.6)分]、排便功能评分[(76.6±10.4)分和(87.5±10.3)分]均高于术前,腹腔镜组术后结肠癌患者疼痛、饮食受限、焦虑、排便功能评分均高于开腹组,差异均有统计学意义(P<0.05)。结论腹腔镜与开腹手术治疗结肠癌均有较好的临床疗效,而腹腔镜手术预后和生活质量更好。
Objective To investigate the clinical effect of laparoscopic surgery versus laparotomy in the treat-ment of colon cancer and to evaluate the patients＆#39; postoperative quality of life. Methods Sixty patients of colon cancer in our hospital from May 2014 to March 2016 were enrolled and divided into two groups by different operation methods：lap-aroscopic surgery group （30 patients） and laparotomy group （30 patients）. The clinical effects, prognosis, and quality of life before and after operation were detected. Results The number of dissected lymph nodes, length of removed speci-men, and tumor distal length were （25.1±5.0） cm, （17.8±5.4） cm, （3.1±1.5） cm in laparotomy group, versus （24.8±5.6） cm, （16.8±5.3） cm, （2.8±1.4） cm in laparoscopic surgery group （P〉0.05）. Before operation, the scores of pain, dietary restric-tions, anxiety, bowel function were （66.8 ± 10.8）, （66.2 ± 10.1）, （66.2 ± 10.1）, （66.1 ± 10.2） in laparotomy group, versus （67.5±10.4）, （67.1±10.3）, （67.6±10.3）, （67.1±10.3） in laparoscopic surgery group （P〉0.05）. The local recurrence rate, dis-tant metastasis rate were 6.7%, 6.7%in laparoscopic surgery group, significantly lower than 26.7%, 26.7%in laparotomy group. After operation, the scores of pain, dietary restrictions, anxiety, bowel function were significantly higher than those before operation, which were （76.8 ± 10.1）, （76.6 ± 10.2）, （76.3 ± 10.5）, （76.6 ± 10.4） in laparotomy group and （87.9 ± 10.5）, （87.5±10.4）, （87.9±10.6）, （87.5±10.3） in laparoscopic surgery group, and the scores in the laparoscopic surgery group were significantly higher than those in laparotomy group （P〈0.05）. Conclusion Laparoscopic surgery and laparotomy both have good clinical effect in the treatment of colon cancer, but the former brings better prognosis and higher quality of life.
出处
《海南医学》
CAS
2017年第20期3312-3314,共3页
Hainan Medical Journal
基金
梅州市科技计划项目(编号:2016B107)
关键词
腹腔镜
开腹手术
结肠癌
临床疗效
生活质量
Laparoscopic
Laparotomy
Colon cancer
Clinical effects
Quality of life
