摘要
目的观察大柴胡汤合桂枝茯苓丸治疗痰热瘀结型多囊卵巢综合征(PCOS)的临床疗效。方法选取2015年1月—2016年12月我院门诊的肥胖型痰热瘀结证PCO S患者68例,随机分为对照组和观察组各34例。对照组口服达英-35治疗;在对照组的基础上,加用大柴胡汤合桂枝茯苓丸加减治疗,分别观察治疗前及治疗3个月后患者体重指数(BMI)、痤疮、性激素(LH、FSH、LH/FSH、T)、空腹血糖(FPG)、空腹胰岛素(FINS)、总胆固醇(TC)、甘油三酯(TG)的差异。结果观察组的BMI、痤疮评分和LH、T、FPG、FINS、TC、TG在治疗前后对比,P<0.05,差异均有统计学意义;FSH在治疗前后对比,P>0.05,差异无统计学意义。结论运用中西医治疗治疗痰热瘀结型征PCOS患者,对于减轻体质量、改善痤疮、降低LH、T及降糖、降脂方面,疗效颇显,可达到调节机体内分泌,改善胰岛素抵抗,减轻PCOS症状的目的。
Objective To observe the clinical effect of Dachaihu decoction and Guizhi Fuling pill in the treatment of polycystic ovary syndrome of phlegm heat stasis syndrome type. Methods From January 2015 to December 2016 in our hospital outpatient, 68 cases of PCOS patients with obese type of stagnation of phlegm and heat syndrome were randomly divided into control group and observation group, with 34 cases in each group. The control group was given oral Diane-35. The observation group was given Dachaihu decoction and Guizhi Fuling pill on the basis of the control group for 3 months. After 3 months of treatment, difference on BMI, acne, sex hormones（LH, FSH, LH/FSH, T）, fasting blood glucose（FPG）, fasting insulin（FINS）, total cholesterol（TC）,triglyceride（TG） were observed. Results The results of the study group before treatment and compared after 3 months, BMI, LH, T,acne score and FPG, FINS, TC, TG, P〈0.05, were statistically significant. FSH in comparison before and after treatment P〉0.05, and there was no statistical significance. Conclusion The traditional Chinese medicine and Western medicine in the treatment of PCOS of phlegm heat stasis syndrome type can reduce body weight, improve acne, reduce LH, T and blood glucose and lipid level, has significant effect, can regulate endocrine, improve insulin resistance, and alleviate the symptoms of PCOS.
出处
《中国中医药现代远程教育》
2017年第21期82-84,共3页
Chinese Medicine Modern Distance Education of China
关键词
多囊卵巢综合征
痰热瘀结证
大柴胡汤
桂枝茯苓丸
癥瘕
月经不调
polycystic ovary syndrome
phlegm heat stasis syndrome
Dachaihu decoction
Guizhi Fuling pill
abdominal mass
irregular menstruation
