摘要
目的:探讨如意金黄散外敷治疗黄体酮肌内注射后所致人工脂膜炎的临床疗效。方法:选择2007年3月—2016年3月在北京大学第三医院进行体外受精-胚胎移植(IVF-ET)和冻融胚胎移植(FET)中使用肌内注射黄体酮后确诊为人工脂膜炎的患者63例,2例脱落。用队列研究方法按1∶1比例随机分为治疗组31例和对照组30例。治疗组用如意金黄散陈醋调制后外敷治疗,对照组用50%硫酸镁湿热敷,用药7 d为1疗程,治疗3个疗程,每个疗程末用秩和检验评价治疗效果。结果:经过3个疗程治疗,每疗程末均进行2组患者的疗效比较,差异有统计学意义(Z分别为-4.064,-2.965,-4.554,均P<0.05)。结论:如意金黄散外敷治疗人工脂膜炎可以明显改善临床症状,促进病情恢复。
Objective：To observe the clinical efficacy of Ruyijinhuang Pulvis in treatment of facititial panniculitis following intramuscular injection of progesterone. Methods：Using cohort study, 63 facititial panniculitis patients in line with inclusive criteria were randomly assigned to the treatment group（treated with Ruyijinhuang Pulvis, 31 cases） and the control group（treated with Magnesium sulfate, 30 cases）, 2 cases dropped.These facititial panniculitis were followed by the progesterone treatment during their in vitro fertilization-embryo transfer（IVF-ET） or frozen embryo transfer（FET） cycles. Scored symptoms of facititial panniculitis（tissue swelling,induration and rash） were observed before and after treatment. The data was analyzed by SPSS 18.0. Results：All patients were treated for 3 courses of treatment. The therapeutic effect at the end of each course was compared between two groups. There was significant difference in the total therapeutic effect between two groups（Z values were-4.064,-2.965 and-4.554 for three courses, all P〈0.05）. Conclusions：Ruyijinhuang Pulvis could significantly improve clinical symptom of facititial panniculitis and promote the recovery.
出处
《国际生殖健康／计划生育杂志》
CAS
2017年第6期463-465,共3页
Journal of International Reproductive Health/Family Planning
基金
国家自然科学基金(81471427)
关键词
如意金黄散
脂膜炎
孕激素类
人工脂膜炎
Ruyi jinhuang powders
Panniculitis
Progestins
Factitial panniculitis
