摘要
目的探讨两种气囊压力带在辅助下肢深静脉血栓(DVT)溶栓治疗中阻断浅静脉的压力值范围,既能有效溶解血栓又能提高患者舒适度,为实施个体化、规范护理流程提供依据。方法 80例下肢DVT患者分为改良型气囊压力带组(研究组)和传统表式血压计袖带组(对照组),每组40例,两组均行输液泵持续泵入尿激酶经足背静脉顺行溶栓治疗,每日尿激酶用量相同。两组患者阻断下肢浅静脉血流的压力值在下肢静脉造影时测定,即下肢深静脉显影时的气囊压力值。对比分析两组患者的腿围消肿率、平均血栓清除率及舒适度等指标。结果研究组下肢浅静脉血流阻断压力为65~75 mm Hg,平均(70±5)mm Hg;对照组下肢浅静脉血流阻断压力值为60~85 mm Hg,平均值(70±10)mm Hg。两组患者的腿围消肿率、不同时间点的平均血栓清除率、舒适度评分均存在显著差异(P<0.05),研究组均优于对照组。结论与传统表式血压计袖带相比,应用改良型气囊压力带阻断下肢浅静脉血流可以获得较好的溶栓疗效,且治疗过程中患者舒适度较高。
Objective To investigate the optimal pressure range produced by two types of air pressure cuff in order to block superficial vein to assist thrombolytic therapy for deep venous thrombosis （DVT） of lower extremity, which can effectively dissolve the thrombus as well as improve the patient＇s comfort, and to provide useful basis for the implementation of individualized and standard nursing process. Methods A total of 80 patients with lower limb DVT were randomly and equally divided into the modified air pressure cuff group （study group, n=40） and the traditional standard sphygmomanometer cuff group （control group, n=40）. Thrombolytic therapy by using continuous intravenous infusion of urokinase via the dorsalis pedis vein with infusion pump was performed in all patients of both groups. The daily dose of urokinase was the same. The pressure value to obstruct lower limb superficial venous blood flow, that was the airbag pressure value when the deep veins of lower limb became visualized on venography, was determined. Leg swelling fade-away rate, mean thrombus clearance rate and patient＇s comfort degree, etc. were calculated, and the results were compared between the two groups. Results In the study group, the pressure value to block superficial venous blood flow of lower limb was 65-75 mmHg with a mean of （70±5） mmHg; which in the control group was 60-85 mmHg with a mean of （70±10） mmHg. The Leg swelling fade-away rate, the mean thrombus clearance rate determined at different time points, and the patient＇s comfort degree of the study group were remarkably better than those of the control group （P〈0.05）. Conclusion Compared to the use of traditional standard sphygmomanometer cuff, the use of modified air pressure cuff to block the lower limb superficial venous blood flow can obtain better thrombolytic effect, meanwhile, the patients can get high comfort degree in the therapeutic process.
出处
《介入放射学杂志》
CSCD
北大核心
2017年第11期1042-1045,共4页
Journal of Interventional Radiology
基金
国家自然科学基金(81541061)
江苏省条件建设与民生科技专项项目(BL2014013)
南京市医学科技发展项目(ZKX15030)
南京市卫生局科技发展项目(YKK13105)
关键词
下肢深静脉血栓形成
溶栓治疗
浅静脉
血流阻断
lower limb deep venous thrombosis
thrombolytic therapy
superficial vein
blood flow occlusion
