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肝巨噬细胞在乙醇性脂肪肝发病过程中的作用研究进展 被引量:1

Progress in role of hepatic macrophages in the pathogeny of alcoholic fatty liver disease
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摘要 在我国的乙醇性脂肪肝(AFL)患者人数与日俱增,已达到不容忽视的水平。本文将以固有的枯否细胞(KCs)和单核细胞来源的巨噬细胞(RHMs)为主,概述肝巨噬细胞在AFL中的变化,进而为AFL的治疗提供可能的新靶点和新方法。 The number of alcoholic fatty liver( AFL) cases have been increasing to a level that cannot be ignored in China. In this paper,we will review the change of hepatic macrophages in the development of alcoholic fatty liver disease with emphasis on resident Kupffer cells( KCs) and recruited hepatic macrophages( RHMs). This paper provides possible targets and treatments for alcoholic fatty liver disease.
出处 《中国临床药理学杂志》 CAS CSCD 北大核心 2017年第21期2202-2205,共4页 The Chinese Journal of Clinical Pharmacology
基金 国家自然科学基金面上基金资助项目(81573690) 国家自然科学基金重大国际(地区)合作研究基金资助项目(81320108029)
关键词 乙醇性脂肪肝 巨噬细胞 枯否细胞 单核细胞来源的巨噬细胞 固有免疫 alcoholic fatty liver macrophage Kupffer cell recruited hepatic macrophage innate immunity
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