摘要
目的探讨硫酸镁结合硝苯地平在妊娠期高血压疾病治疗中的疗效和安全性。方法选取2014年1月-2016年6月我院妊娠期高血压病孕妇81例作为研究对象,按治疗方法不同分为2组,其中对照组29例,应用硫酸镁治疗;观察组52例,应用硫酸镁联合硝苯地平治疗;比较两组疗效和患者血压、24h蛋白尿总量水平及不良反应。结果观察组总有效率100%,明显优于对照组的82.76%,且观察组的治愈率与对照组比较明显较高,差异有统计学意义（P〈0.05）。对照组不良反应率为17.24%,观察组不良反应率为3.85%;差异有统计学意义（P〈0.05）。结论硫酸镁结合硝苯地平治疗妊娠期高血压疾病的效果更显著,安全性更好。
Objective To investigate the effcacy and safety of magnesium sulfate combined with Nifedipine in the treatment of pregnancy-induced hypertension. Methods 81 cases of patients with pregnancy-induced hypertension treated in our hospital from March 2014 to June 2016 were selected as object. All patients were divided into two groups, 29 patients in control group treated with magnesium sulfate and 52 in observed group treated with magnesium sulfate combined with Nifedipine. The clinical efficacy, blood pressure, total proteinuria and adverse reactions were compared between the two groups. Results The total effective rate of observation group was 100%, which was signifcantly better than that of the control group 82.76%. The cure rate of the observation group was significantly higher than that of the control group （P〈0.05）. The adverse reaction rate was 17.24% in the control group and 3.85% in the observation group, respectively. The difference was statistical significantly （P〈0.05）. Conclusion Magnesium sulfate combined with Nifedipine used in the treatment of pregnancy-induced hypertension had better effcacy and more safe.
出处
《实用妇科内分泌电子杂志》
2016年第12期4-6,共3页
Electronic Journal of Practical Gynecological Endocrinology
关键词
妊娠期高血压疾病
联合治疗
盐酸硫酸镁
硝苯地平
Pregnancy-induced hypertension
Combined therapy
Magnesium chloride
Nifedipine
