摘要
目的观察丁苯酞早期治疗对后循环卒中患者康复效果的影响。方法选择医院收治的104例后循环缺血性卒中患者,发病24 h内接受丁苯酞治疗的为观察组,发病24~72 h接受丁苯酞治疗的为对照组,同时两组均给予常规治疗。分别在治疗前后,检测患者双侧椎动脉血流速度,测定ADAS-Cog评分及NIHSS评分,统计治疗后6个月内严重并发症发生情况及预后。结果治疗14 d后,两组双侧椎动脉血流速度均升高,但观察组的升高幅度大于对照组(P<0.05)。治疗14 d后,两组ADAS-Cog和NIHSS评分均显著降低(P<0.05),且观察组明显低于对照组(P<0.05)。6个月后,两组的致残率及致死率无明显差异(P>0.05),但观察组的康复率明显高于对照组,颅内出血率明显低于对照组(P<0.05)。结论采用丁苯酞早期治疗后循环缺血性卒中,可提高患者双侧椎动脉血流速度,减少颅内出血,促进患者康复。
Objective to observe the impacts of early treatment with butyphthalide on rehabilitation effects in the patients with posterior circulation stroke. Methods A total of 104 patients with posterior circulation ischemic stroke admitted to our hospital were selected and divided into an observation group and a control group according to the time of butyphthalide treatment. The observation group received butyphthalide treatment within 24 h upon attack and the control group during 24-72 h upon attack. The two groups were treated with conventional therapy. The bilateral arterial blood flow velocity of the patients was detected before and after the treatment respectively; ADAS-Cog scores and NIHSS scores were determined; the incidence of severe complications within six months after the treatment and the prognosis were recorded, Results After 14 days of treatment, the bilateral arterial blood flow velocity in the two groups increased, but the increase in the observation group was greater than that in the control group （P 〈 0.05）; the ADAS- Cog scores and NIHSS scores in the two groups decreased significantly （P 〈 0.05）, and the scores in the observation group were much lower than those in the control group （P 〈 0.05）. Six months later, the disability rate and fatality rate showed no significant difference between the two groups （P 〉 0.05）, but the rehabilitation rate in the observation group was much higher than that in the control group, and the intracranial bleeding rate was much lower than that in the control group （P 〈 0.05）. Conclusion The early treatment of posterior circulation ischemic stroke with butyphthalide can improve the bilateral arterial blood flow velocity, reduce intracranial bleeding and promote rehabilitation.
出处
《西南国防医药》
CAS
2017年第11期1168-1170,共3页
Medical Journal of National Defending Forces in Southwest China
关键词
早期
丁苯酞
后循环
卒中
疗效
early treatment
butyphthalide
posterior circulation
stroke
effect
