摘要
目的探讨药物对常用临床检验标本的干扰因素及应对措施。方法选择我院2015年1月20日~2017年6月20日收治的300例患者,对其基本资料进行回顾性分析,探讨药物对临床检验标本检测造成的干扰。结果 300例患者中,白细胞(1.33%)、血红蛋白(0.33%)、血小板(1.00%)、嗜酸粒细胞(0.33%)、凝血因子Ⅱ时间(0.33%)、出血时间(0.33%)等血液检测结果均受到所用药物的干扰;所用药物对尿液检验的颜色(0.67%)、密度(0.33%)、白细胞(0.67%)、蛋白(0.67%)、红细胞(0.67%)、葡萄糖(0.67%)、胆红素(1.00%)、尿胆原(1.00%)造成影响;在大便检测结果中,给予磷酸亚铁、胃必治治疗4例(1.33%)的患者出现假阳性结果,3例(1.00%)给予维生素C治疗的患者出现大便隐血试验阳性减弱,2例(0.67%)假阴性结果。结论临床上应综合分析患者短时间内的用药情况,以便进一步提高将药物对于检验标本检验结果的准确性,从而对疾病的诊断与治疗提供相关的判定依据。
Objective To investigate the interference factors and countermeasures of drugs on common clinical samples. Methods 300 patients who were admitted to our hospital from January 20 in 2015 to June 20 in 2017 were selected. The basic data were retrospective analyzed.The interference caused by the drugs on the detection of clinical test samples was investigated.Results In 300 patients,the blood test results were interfered by the drugs used,such as white blood cells （1.33%）,hemoglobin （0.33%）,platelet （1.00%）,eosinophil （0.33%）,coagulation factor Ⅱ time （0.33%）,bleeding time （0.33%）.The drugs used affected the results of urine tests,such as color （0.67%）,density （0.33%）,white blood cells （0.67%）,protein （0.67%）,red blood cells （0.67%）,glucose （0.67%）,bilirubin （1.00%）,urobilinogen （l.00%）.In stool test results,4 cases （1.33%） were treated with ferrous phosphate and Bismuth Aluminate Compound Tablet were found false positive results.3 cases （1.00%） were given vitamin C and the positive results of fecal occult blood test were weakened, and 2 cases （0.67%） showed false negative results.Conclusion Clinically,the short-term medication in the patients should be analyzed comprehensively,to facilitate the further improvement of the accuracy of drugs on the test results of samples,so as to provide the relevant judgment basis for the diagnosis and treatment of the disease.
出处
《中国当代医药》
2017年第30期129-132,共4页
China Modern Medicine
关键词
干扰因素
检验标本
药物
措施
Interference factor
Test sample
Drug
Measure
