摘要
目的探讨利多卡因联合硝酸甘油预防桡动脉痉挛的临床效果。方法选取2017年1~8月我院收治的77例经桡动脉径路行CAG患者作为研究对象,采用单双号分组法将其分为对照组(n=38)与试验组(n=39)。对照组患者仅使用200μg硝酸甘油治疗,试验组患者则使用20 mg盐酸利多卡因联合200μg硝酸甘油治疗。比较两组患者的桡动脉痉挛发生率、穿刺成功率、穿刺次数、手术成功率以及疼痛程度(VAS)评分情况。结果试验组患者的桡动脉痉挛发生率(0.00%)低于对照组(13.16%),差异有统计学意义(P<0.05);穿刺成功率(97.44%)、穿刺次数[(1.05±0.36)次]、手术成功率(89.74%)均明显高于对照组[73.68%,(2.15±0.34)次,68.42%],差异有统计学意义(P<0.05);试验组患者的VAS评分[(3.56±0.54)分]明显低于对照组[(5.64±0.24)分],差异有统计学意义(P<0.05)。结论利多卡因联合硝酸甘油可降低CAG患者的桡动脉痉挛发生率,穿刺成功率高,且疼痛感低,值得推广应用。
Objective To investigate the clinical effect of Lidocaine combined with Nitroglycerin in the prevention of radial artery spasm.Methods 77 patients with transradial coronary angiography from January to August 2017 treated in our hodpital were selected as study objects.They were divided into control group （38 cases） and test group （39 cases） by single and even number grouping method.Control group was treated with 200μg Nitroglycerin alone,and the test group was treated with 20 mg Lidocaine combined with 200μg Nitroglycerin.The incidence rate of radial artery spasm,puncture success rate,puncture frequency,operation success rate and pain degree （VAS） score of two groups were compared and analyzed.Results The incidence of radial artery spasm in the test group （0.00%） was lower than that in the control group （13.16%）,the difference was statistically significant （P〈0.05）.The puncture success rate （97A4%）,puncture frequency [（1.05±0.36） times],operation success rate （89.74%） in the test group were lower than those in the control group [73.68%, （2.15±0.34） times,68.42%],the differences were statistically significant （P〈0.05）.The VAS score in the test group [（3.56±0.54） points] was significantly lower than that in the control group [（5.64±0.24） points],and the difference was statistically significant （P〈0.05）.Conclusion Lidocaine combined with Nitroglycerin can reduce the incidence of radial artery spasm in patients with CAG,with high success rate of puncture and the pain is low.It is worthy of clinical application.
出处
《中国当代医药》
2017年第30期102-104,共3页
China Modern Medicine
