摘要
目的探讨复合异丙酚麻醉诱导时舒芬太尼抑制患者喉罩插管反应的药效学价值。方法收集我院2014年1月至2015年12月入院的80例行全麻非腔镜手术患者随机分为两组,研究组患者采取异丙酚诱导+舒芬太尼,对照组患者采取异丙酚诱导+芬太尼,比较两组患者不同时点脑电双频指数、血压与心率、不良反应与诱导时间。结果两组患者不同时点脑电双频指数、血压与心率均不存在明显差异,不具有统计学意义(P>0.05);研究组患者总体不良反应发生率(12.5%)明显低于对照组(32.5%),存在明显差异,具有统计学意义(P<0.05);两组患者麻醉诱导时间不存在明显差异,不具有统计学意义(P>0.05)。结论复合异丙酚麻醉诱导时舒芬太尼抑制患者喉罩插管反应的药效学价值较高,具有借鉴性。
Objective To investigate the pharmacodynamic value of sufentanil inhibiting laryngeal mask insertion reaction in the induction of propofol anesthesia. Methods 80 patients undergoing general anesthesia were randomly divided into two groups： research group received propofol induced＋sufentanil and control group received propofol induced ＋fentanyl, compared between two groups of patients at different points of bis, blood pressure and heart rate, adverse reactions and induction time. Results There was no significant difference in blood pressure and heart rate between the two groups at different time points（P〉0.05）. The incidence of overall adverse reaction in research group was significantly lower than that in control group, and there was significant difference（P〈0.05）. There was no significant difference in the induction time of anesthesia between the two groups（P〉0.05）. Conclus ion The inhibitory effect of sufentanil on the intubation of laryngeal mask is high in the induction of propofol anesthesia.
出处
《中国药物警戒》
2017年第10期587-589,共3页
Chinese Journal of Pharmacovigilance
关键词
异丙酚
舒芬太尼
喉罩插管反应
麻醉诱导
propofol
sufentanil
laryngeal mask intubation reaction
induction of anesthesia
