摘要
Barrett食管(BE)是常见的上消化道动力障碍性疾病,是胃食管反流病(GERD)的严重并发症。BE发生、发展与多种因素有关,是抗反流防御机制减弱和反流物对食管黏膜攻击作用的共同结果,其中上消化道动力异常起有重要作用,包括食管胃连接处(EGJ)高压带功能障碍、一过性下食管括约肌松弛增加、食管体部运动功能障碍、胃排空延迟、食管裂孔疝等。本文就BE的上消化道动力异常作一综述。
Barrett＇s esophagus（ BE） is a commonly seen upper gastrointestinal motility dysfunction disease,and it is a serious complication of gastroesophageal reflux disease（ GERD）. The occurrence and development of BE are related to multiple factors,and is the result of weakening of anti-reflux defense mechanism and attack of reflux contents on esophageal mucosa. Among them,the dysfunction of upper gastrointestinal motility plays an important role,including dysfunction of esophagogastric junction（ EGJ） high-pressure zone,increased transient lower esophageal sphincter relaxation,esophageal body movement dysfunction,delayed gastric emptying and esophageal hiatal hernia. This article reviewed the dysfunction of upper gastrointestinal motility in BE.
出处
《胃肠病学》
2017年第10期623-626,共4页
Chinese Journal of Gastroenterology
关键词
BARRETT食管
胃食管反流
动力障碍
食管括约肌
下段
胃排空
疝
食管裂孔
Barrett Esophagus
Gastroesophageal Reflux
Motility Dysfunction
Esophageal Sphincter, Lower
Gastric Emptying
Hernia, Hiatal
