摘要
We developed a simple and efficient Cu（II）-catalyzed ligand-free oxidation of diarylmethanes and secondary alcohols using 70% ten-butyl hydroperoxide （TBHP） in water. A series of diarylmethanes were directly oxidized into diaryl ketones in 67%--98% yields. Additionally, various secondary alcohols were also transformed into the desired products in 48%--98% yields. Importantly, the catalytic system in the absence of any organic solvent, surfactant, or phase transfer agent, had a wide substrate scope and a high tolerance for various functional groups.
We developed a simple and efficient Cu（II）-catalyzed ligand-free oxidation of diarylmethanes and secondary alcohols using 70% ten-butyl hydroperoxide （TBHP） in water. A series of diarylmethanes were directly oxidized into diaryl ketones in 67%--98% yields. Additionally, various secondary alcohols were also transformed into the desired products in 48%--98% yields. Importantly, the catalytic system in the absence of any organic solvent, surfactant, or phase transfer agent, had a wide substrate scope and a high tolerance for various functional groups.
基金
We gratefully acknowledge financial support of this work by the National Natural Science Foundation of China （No. 21563025）, Shihezi University Training Programme for Distinguished Youth Scholars （No. 2014ZRKXJQ05）, and Start-Up Foundation for Young Scientists of Shihezi University （RCZX201408）.
