摘要
目的探讨血清中PCT和中性粒细胞CD64比例对小儿败血症患者的诊断及预后的评价价值。方法收集2015年9月-2016年9月确诊为败血症的患儿58例为观察组,分为细菌培养阳性组(37例)和细菌培养阴性组(21例);另选择无感染患儿37例为对照组,探讨患者血清中PCT和中性粒细胞CD64水平对小儿败血症的诊断价值及对患者预后的诊断价值。结果血培养阳性组患儿CD64、PCT均高于血培养阴性组和对照组,差异有统计学意义(P<0.05)。PCT+CD64联合的诊断效能较高,诊断的灵敏度、特异度、阳性预测值、阴性预测值均高于单独PCT和CD64进行败血症的诊断效能。PCT、CD64是患者心血管事件的独立风险因素(P<0.05)。结论血清中PCT和中性粒细胞CD64水平有助于小儿败血症的诊断,有助于判断患者预后。
Objective To investigate the value of serum PCT and neutrophil CD64 ratio in the diagnosis and prognosis of neonatal septicemia. Methods 58 cases diagnosed as sepsis were enrolled in the observation group during September 2015-September 2016 and divided into the positive group（ 37 cases） and the negative group（ 21 cases）; 37 cases of non infected patients were selected as the control group,to explore the value of serum PCT and neutrophil CD64 level in the diagnosis of neonatal septicemia and the prognosis in patients. Results CD64 and PCT in the positive group were both significantly higher than that of the negative group and the control group,with the differences statistically significant（ P〈0. 05）. The combined diagnostic efficiency of PCT ＋ CD64 was higher,with the sensitivity,specificity,positive predictive value and negative predictive value higher than the single diagnosis of PCT and CD64. The results suggested that PCT and CD64 were independent risk factors for cardiovascular events. Conclusion The levels of PCT and neutrophil CD64 in serum are helpful to the diagnosis of neonatal septicemia,which is helpful to judge the prognosis of the patients.
出处
《中国卫生检验杂志》
CAS
2017年第20期2950-2952,共3页
Chinese Journal of Health Laboratory Technology
