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中度强化胰岛素治疗对行非体外循环心脏不停跳冠脉搭桥术患者预后的影响 被引量:5

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摘要 目的:探讨中度强化胰岛素治疗对非体外循环心脏不停跳冠脉搭桥术(OPCAB)术后早期预后的影响。方法:行OPCAB的患者72例随机分为A、B、C 3组,每组24例,A组为胰岛素一般治疗,B组为中度胰岛素强化治疗,C组为强化胰岛素治疗,对术后早期乳酸、心律失常、机械通气时间和低血糖发生率进行统计。结果:A组乳酸水平2.3±0.95 mmol/L、术后心律失常发生率33.3%及术后机械通气时间9.42±3.76 h,B组分别为1.9±0.99 mmol/L、8.3%、7.41±1.55 h,C组分别为1.6±0.45 mmol/L、12.5%、7.28±1.47 h,B组、C组与A组乳酸水平、术后心律失常发生率及术后机械通气时间比较,差异均具有统计学意义(P<0.05)。B组与C组术后乳酸、术后心律失常率、机械通气时间之间差异无统计学意义(P>0.05),但低血糖发生率差异具有统计学意义(P<0.05)。结论:非体外循环冠脉搭桥术患者围手术期采用强化胰岛素治疗及中度强化胰岛素治疗控制血糖均可改善患者早期预后,但强化胰岛素治疗有发生低血糖风险,中度胰岛素强化治疗更可取。
出处 《交通医学》 2017年第4期345-346,349,共3页 Medical Journal of Communications
基金 江苏省六大人才高峰资助项目(WSW-085)
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