摘要
按照化学结构分类简要介绍抗真菌药物的作用机制、药效学、独特的药代动力学以及目前相关指南对于曲霉病、念珠菌病等的管理。重点介绍了三种新上市的抗真菌药物,如艾沙康唑、艾氟康唑、Tavaborole。也介绍了某些抗真菌药物所具有的非抗真菌作用。
In the paper,according to the chemical structure of antifungal agents,the mechanism of action,pharmacodynamics,unique pharmacokinetic and the current guidelines for the management of aspergillosis,candidiasis etc were briefly introduced. Three kinds of new antifungal drugs,namely,Isavuconazonium,Efinaconazole and Tavaborole were particularly demonstrated. The non-antifungal effects of some antifungal agents were also introduced.
出处
《皮肤科学通报》
2017年第5期540-550,共11页
Dermatology Bulletin
基金
北京市自然科学基金资助项目(7164255)
