摘要
目的观察胎粪吸引管气管内吸引防治羊水Ⅲ度粪染且无活力新生儿胎粪吸入综合征(MAS)的临床效果。方法 81例羊水Ⅲ度粪染且无活力新生儿,随机分为治疗组(40例)和对照组(41例)。对照组采用气管内吸痰管与负压器相连进行气管内吸引治疗,治疗组采用胎粪吸引管气管内吸引治疗。比较两组患儿的MAS发生率、呼吸机辅助通气率、治愈率、死亡率及住院时间。结果治疗组MAS发生率30.0%、重症MAS发生率2.5%均低于对照组53.7%、17.1%,差异均具有统计学意义(P<0.05)。治疗组辅助通气率0低于对照组14.6%,差异具有统计学意义(P<0.05)。治疗组治愈率95.0%高于对照组61.0%,差异具有统计学意义(P<0.01);两组死亡率比较,差异无统计学意义(P>0.05)。治疗组住院时间(5.6±1.3)d短于对照组(8.1±1.2)d,差异具有统计学意义(P<0.01)。结论胎粪吸引管气管内吸引防治羊水Ⅲ度粪染且无活力新生儿MAS效果显著,新生儿MAS发生率、重症MAS发生率、呼吸机辅助通气率低,住院时间短,治愈率高,能够减轻患儿的痛苦及家庭的经济负担,值得临床推广与应用。
Objective To observe the clinical effect of intratracheal aspiration with meconium aspiration tube for prevention and treatment of inactive newborns with meconium aspiration syndrome（MAS）and amniotic fluid Ⅲ degree fecal stain. Methods A total of 81 inactive newborns with amniotic fluid Ⅲ degree fecal stain were randomly divided into treatment group（40 cases） and control group（41 cases）. The control group was treated with intratracheal aspiration with tracheal suction tube connected with the negative pressure device, and the treatment group was treated with intratracheal aspiration with meconium aspiration tube. Comparison were made on incidence of MAS, ventilator-assisted ventilation, cure rate, mortality and hospitalization time between two groups. Results The treatment group had lower incidence of MAS as 30.0%, incidence of severe MAS as 2.5% than 53.7% and 17.1% in the control group, and the difference was statistically significant（P〈0.05）. The treatment group had lower auxiliary ventilation rate as 0 than 14.6% in the control group, and the difference was statistically significant（P〈0.05）. The treatment group had higher cure rate as 95.0% than 61.0% in the control group, and the difference was statistically significant（P〈0.01）. Both groups had no statistically significant difference in death rate（P〉0.05）. The treatment group had shorter hospitalization time as（5.6±1.3） d than（8.1±1.2） d in the control group, and the difference was statistically significant（P〈0.01）. Conclusion Intratracheal aspiration with meconium aspiration tube shows remarkable effect in prevention and treatment of inactive newborns with MAS and amniotic fluid Ⅲ degree fecal stain, and it can reduce incidence of MAS and severe MAS, lower ventilator assisted ventilation rate, shorten hospitalization time and improve cure rate, relieve pain and financial burden of the family. It is worthy of clinical promotion and application.
出处
《中国现代药物应用》
2017年第20期1-3,共3页
Chinese Journal of Modern Drug Application
基金
2015年揭阳市场卫生和计划生育局医学科学技术研究立项项目和推广应用新技术新项目(项目编号:201500096)
关键词
胎粪吸引管
无活力新生儿
胎粪吸入综合征
Meconium aspiration tube
Inactive newborn
Meconium aspiration syndrome
