摘要
目的探讨妊娠合并急性胰腺炎(acute pancreatitis in pregnancy,APIP)对妊娠结局的影响因素。方法回顾分析2001年1月至2017年1月于中山大学附属第一医院确诊的34例APIP患者的临床资料,并根据分级标准将其分为轻度急性胰腺炎(MAP组23例)和重度急性胰腺炎(SAP组11例),比较两组患者的一般资料、临床表现、诊疗措施及妊娠结局。结果两组患者中高脂血症[SAP组(7/11例)和MAP组(4/23例),P=0.016],新生儿窒息发生率[SAP组(4/11例)和MAP组(1/23例),P=0.038)],分娩孕周[SAP组(32.7±5.6)周和MAP组(37.0±3.8)周,P=0.035];两组患者其余指标未发现统计学差异。结论甘油三酯或胆固醇增高与SAP有关,SAP病情危重,严重损害母胎健康,因此妊娠期应加强对血脂水平的监控。
Objective To investigate how acute pancreatitis affect the pregnancy outcome.Methods A retrospective study was conducted in 34 pregnant women with acute pancreatitis in The First Affiliated Hospital of Sun Yat-sen University from January 2001 to January 2017. The patients were divided into mild acute pancreatitis（ MAP） group（ 23 cases） and severe acute pancreatitis（ SAP） group（ 11 cases）,and the general information, clinical symptoms, treatment and pregnancy outcome were analyzed.Results The incidence of hyperlipidemia and neonatal asphyxia in SAP group were（ 7/11 cases） and（ 3/11 cases）,which were significantly higher than those in MAP group（ 4/23） and（ 1/23）,P = 0. 016 and P = 0. 038,respectively. Compare with MAP group,the gestational weeks of delivery in SAP group was lower（ 32. 7 ± 5. 6 weeks vs 37. 0 ± 3. 8 weeks,P = 0. 035）. There was no statistical significance of other indicators in the two groups. Conclusions SAP was associated with higher triglyceride and hyperlipidemia.SAP is the serious condition and harm to maternal-fetal heath seriously,so the level of blood lipids should be monitored and controlled strictly during pregnancy.
作者
丁文静
仇希雯
王子莲
Ding Wenjing Qiu Xiwen Wang Zilian.(Department of Obstetrics and Gynecology, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou 510080, China)
出处
《中华产科急救电子杂志》
2017年第2期112-117,共6页
Chinese Journal of Obstetric Emergency（Electronic Edition）
关键词
妊娠
高危
胰腺炎
急性坏死性
高脂血症
Pregnancy, high-risk
Pancreatitis, acute necrotizing
Hyperlipidemias
