摘要
目的探讨Pierre Robin序列征患儿的临床特点及随访情况,为合理诊治提供依据。方法回顾性分析2012年1月~2017年3月本院新生儿病房收治的Pierre Robin序列征患儿的临床资料,总结患儿临床特点和诊治要点。结果 15例Pierre Robin序列征患儿均具有小下颌畸形、舌后坠及喂养困难、呼吸困难等典型临床特征,12例有腭裂。15例患儿按临床分级给予综合治疗,其中5例放弃治疗后死亡。10例病情好转出院的患儿中,2例失访,8例随访患儿中6例生长发育指标与正常同龄儿童相仿,2例生长发育较正常同龄儿童落后。结论临床医生深刻认识Pierre Robin序列征的临床特征有助于早期诊断本病,按本病分级制定个体化治疗方案能有效改善患儿预后。
Objective To investigate the clinical characteristics and follow-up of children with PierreRobin sequencesigns, and to provide evidence for rational diagnosis and treatment. Methods The clinical data of children with Pierre Robin sequencesignsadmitted in our neonatal ward from January 2012 to March 2017 were analyzed retrospectively,the clinical features and diagnosis and treatment of children were summarized. Results 15 cases of Pierre Robin sequencesigns were with micrognathia,tongue fall and feeding difficulties,breathing difficulties and other typical clinical features,there were 12 cases with cleft palate.15 children were given comprehensive treatment according to clinical classification,5 cases of them died after giving up treatment.Of the 10 children who were discharged from the hospital,2 cases were lost and 8 cases were followed up.6 cases of the children were similar to those of normal children of the same age,and 2 cases were less developed than those of normal children of the same age. Conclusion Clinicians have a profound understanding of the clinical features of Pierre Robin sequencesigns,which is helpful for the early diagnosis of this disease.According to the classification of the disease,it is possible to develop an individualized treatment nlan to improve the prognosis of the children.
出处
《中国医药科学》
2017年第20期79-81,共3页
China Medicine And Pharmacy