摘要
目的 观察经尿道前列腺电切术联合内分泌方法治疗中晚期前列腺癌的临床疗效.方法 选取满足该病理周期的患者70例,并随机分为对照组和观察组（每组各35例）,对照组单纯采用传统的内分泌疗法,观察组采取综合疗法实施治疗.对治疗方案实施前后两组患者的国际前列腺症状评分（IPSS评分）、前列腺特异抗原水平（PSA）、剩余的尿量以及最大尿流率以及随访的复发率、转移率以及死亡率进行比较.结果 在治疗以前上述参数均不存在差异（P＞0.05）;而在实施治疗之后上述参数均有明显改善,其中最大尿流率明显提升,其余参数均降低,两组间差异有统计学意义（P＜0.01）.而两组患者的三年病灶转移率、死亡率等参数差异也无统计学意义（P＞0.05）.结论 该疗法可以有效地消解尿路梗阻,并控制癌细胞的进一步生长,治疗不仅安全,同时也相当可靠.
Objective To observe the clinical effect of transurethral resection of the prostate combined with hormonal therapy for advanced prostate cancer.Methods A total of 70 patients who met the pathological cycle were randomly divided into the two groups,35 patients in the control group underwent the traditional endocrine therapy,and 35 patients in the study group underwent combination therapy.International prostate symptom score （IPSS） before and after treatment,prostate-specific antigen （PSA） levels,residual volume and maximum flow rate and the rate of recurrent,the transfer rate and mortality were compared.Results There was no significant difference in these parameters before treatment（P ＞ 0.05）.There were significant differences in maximum urinary flow rate and other parameters after treatment between the two groups （P ＜0.01）.There was no significant difference in 3-years metastases rate,death rate and other parameters between the two groups （P ＞ 0.05）.Conclusions Transurethral resection of the prostate combined with hormonal therapy can effectively eliminate urinary tract obstruction,and control the further growth of cancer cells,the treatment is not only safe,but also very reliable.
出处
《国际泌尿系统杂志》
2017年第5期643-646,共4页
International Journal of Urology and Nephrology
关键词
前列腺肿瘤
尿道
电外科手术
Prostatic Neoplasms
Urethra
Electrosurgery
