摘要
目的了解烟台市某区孕前检查夫妇双方的乙肝感染状况,探讨相关影响因素。方法选择2016年l—l2月在烟台市某区进行孕前检查的475对夫妇作为研究对象,对其填写的家庭档案和检测的乙肝五项检查结果进行分析。结果受检夫妇的乙肝表面抗原(HbsAg)总阳性率为4.21%,乙肝表面抗体(HbsAb)总阳性率58.74%,乙肝五项总全阴率为34.74%;40例HbsAg阳性者,均为夫妇一方HbsAg阳性,占总夫妇数8.42%;性别、年龄、职业、胎次和既往有无接种疫苗,对HbsAg阳性率差异无统计学意义(P>0.05),而女性不同文化程度、职业和既往有无接种疫苗,对其HbsAb阳性率差异有统计学意义(P<0.05),女性文化程度为初中及以下是HbsAb阳性的危险因素(OR=-0.974,P<0.01),而女性职业为教师/公务员/职员为HbsAb阳性的保护因素(OR=0.912,P<0.05)。结论乙肝是影响人群健康的重要因素,孕前检查乙肝五项有利于防止乙肝家庭内部传播和母婴垂直传播。孕前检查夫妇乙肝表面抗体尚待提高,需定期监测乙肝表面抗体滴度,及时加强乙肝疫苗注射,并加强乙肝知识的宣传教育才能有效减少乙肝的发生。
Objectives To understand the situation of HBV infection and influencing factors among pre-pregnancy couples in a district of Yantai city.Methods 475 Pre-pregnancy couples were selected from Jan.to Dec.of2016.Then data was gathered from their family archives and analyzed about age,education,five detection items for Hepatitis B Virus,et al.Results Among the inspected couples,hepatitis B surface antigen（HBsAg）overall positive rate was 4.21%,hepatitis B surface antigen（HBsAb）overall positive rate was 58.74%,and the proportion of five detection items for HBV all negative was 34.74%.40 couples were examined from 475 inspection couples,whose husband or wife＇s HBsAg was positive,the rate was 8.42%.No significant difference was discovered in the proportions of HBsAg positive between cases with different sex,age,education,occupation,parities and inoculation of HBV vaccine（P〈0.05）.But there were statistically significant difference in the rates of HBsAb positive between the tested female with different education,occupation and inoculation of HBV vaccine（P〈0.05）.Females＇ education level below high school was the risk factor of HBsAb positive（OR=-0.974,P〈0.01）,while females＇ occupation being teachers,civil servant or clerks was the protective factor of HBsAb positive（OR=0.912,P〈0.05）.ConclusionsHBV infection damage population health seriously,while the Pre-pregnancy examination has an important role in the prevention of HBV infection.The proportion of HBsAb examination among pre-pregnancy couples needs to be improved.Regular hepatitis B surface antigen（HBsAb）monitoring,vaccination and education may still be necessary for HBV prevention.
出处
《中国社会医学杂志》
2017年第5期463-466,共4页
Chinese Journal of Social Medicine
基金
湖北省人口和计划生育委员会科研立项课题(Js-2100011)
关键词
孕前检查
乙型肝炎
影响因素
Prc-prcgnancy examination
HBV
Influencing factors
