摘要
目的讨论心理干预联合吉西他滨联合替吉奥化疗在胰腺癌根治术后患者中的应用效果。方法随机选取2015年2月～2016年12月本院收治的76例胰腺癌患者并给予胰腺癌根治术,随机分成实验组38例,对照组38例,实验组术后给予心理干预联合吉西他滨与替吉奥化疗方案,对照组给予吉西他滨联合奥沙利铂治疗方案,对2组患者不良反应发生率、治疗有效率和临床受益率进行对比和分析。结果实验组的不良反应发生率和临床受益率明显优于对照组（P〈0.05）,2组治疗有效率差异无统计学意义。结论心理干预联合吉西他滨与替吉奥化疗在胰腺癌根治术后能够提升患者临床受益率,降低不良反应。
Objective To discuss the application effect of psychological intervention combined with gemcitabine combined with S-1 chemotherapy in patients with radical resection of pancreatic cancer in.Methods Randomly selected from February 2015 to December 2016 in our hospital 76 cases of patients with pancreatic cancer and pancreatic cancer radical surgery,were randomly divided into experimental group 38 cases,38 cases in control group were given psychological intervention combined with gemcitabine combined with S-1 chemotherapy after surgery in the experimental group,the control group was given gemcitabine combined with oxaliplatin in the treatment of adverse reactions of the two scheme.Incidence rate and benefit rate were compared and analyzed and the clinical effective rate of treatment.Results The adverse reaction rate and clinical benefit rate of the experimental group were obviously better than that of the control group（P〈0.05）,and there was no significant difference in the treatment efficiency between the two groups.Conclusion The combined chemotherapy with S-1 can improve the clinical benefit rate in radical resection of pancreatic cancer after psychological intervention combined with gemcitabine,reduce adverse reactions,it is worthy of promotion and application.
出处
《中国生化药物杂志》
CAS
2017年第10期284-285,共2页
Chinese Journal of Biochemical Pharmaceutics
关键词
心理干预
吉西他滨
替吉奥
胰腺癌
psychological intervention
gemcitabine
S- 1
pancreatic cancer
