摘要
目的探讨川芎嗪对慢性肾功能衰竭的临床治疗效果。方法选取台州市中心医院2015年10月～2017年1月期间收治的94例慢性肾功能衰竭患者,随机均分为研究组（n=47）和对照组（n=47）,对照组给予临床常规治疗,研究组在常规治疗基础上加用川芎嗪,记录并比较2组治疗前后Scr、Ccr、BUN等肾功能指标变化情况及药物相关不良反应发生率。结果治疗前2组Scr、Ccr、BUN等肾功能指标对比差异无统计学意义;治疗后研究组Scr、Ccr、BUN等肾功能指标改善效果优于对照组（P〈0.05）;治疗期间研究组药物相关各项不良反应发生率与对照组对比差异无统计学意义。结论在常规药物治疗基础上,加用川芎嗪可显著提高慢性肾功能衰竭患者临床疗效。
Objective To investigate the clinical effect of ligustrazine on the treatment of chronic renal failure.Methods 94 patients with chronic renal failure from Oct.2015 to Jan.2017 of Taizhou central hospital were randomly divided into two groups：the study group（n=47） and the control group（n=47）,the control group were received routine clinical treatment,the study group were treated with ligustrazine on the basis of routine treatment.Scr,Ccr,BUN and adverse reaction in the two groups were recorded and compared.Results Scr,Ccr,BUN between the two groups has no statistically difference.After treatment,Scr,Ccr and BUN in the study group were better than those in the control group（P0.05）.There was no significant difference in adverse reactions between the two groups.Conclusion On the basis of routine drug treatment,ligustrazine can significantly improve the clinical efficacy of patients with chronic renal failure,and less adverse reactions.
出处
《中国生化药物杂志》
CAS
2017年第10期223-224,共2页
Chinese Journal of Biochemical Pharmaceutics
关键词
慢性肾功能衰竭
川芎嗪
chronic renal failure
ligustrazine
