摘要
目的:探讨射干麻黄汤治疗小儿咳嗽变异性哮喘的疗效及对血清IgE、IL-4、TNF-α水平的影响。方法:78例咳嗽变异性哮喘患儿随机分为两组,对照组患儿予孟鲁司特钠治疗,观察组患儿在此基础上联合应用射干麻黄汤治疗,比较两组患儿治疗后临床疗效及血清IgE、IL-4、TNF-α水平的变化。结果:观察组咳嗽缓解时间及消失时间均明显短于对照组,差异均有统计学意义(P<0.05);观察组治疗总有效率为97.44%,明显高于对照组的84.62%(P<0.05);治疗后,两组患儿血清IgE、IL-4及TNF-α水平均较治疗前显著下降,且观察组患儿血清IgE、IL-4及TNF-α水平明显低于对照组,差异有统计学意义(P<0.05)。结论:射干麻黄汤治疗小儿咳嗽变异性哮喘可有效降低患儿血清炎症因子水平,促进临床症状的缓解,提高临床疗效。
Objective：To investigate the curative effect of Shegan Mahuang decoction in treating CVA and effect on serum IgE,IL-4,TNF-α.Methods ：78 cases of children with CVA were randomly divided into two groups,the control group were treated with montelukast sodium treatment,the observation group based on the that and combined with shegan mahuang decoction,the clinical curative effect and the changes of serum IgE,IL-4,TNF-αlevels were compared.Results：In the observation group,cough relief time and the disappearance time were significantly shorter than the control group（P 0.05）;the total efficiency of the observation group was 97.44%,significantly higher than the control group（84.62%）,the difference was of statistically significant（P 0.05）;After treatment,serum IgE,IL-4,TNF-αin the two groups were significantly lower,and the observation were lower than the control group,the difference was of statistically significant（P 0.05）.Conclusion：Shegan Mahuang decoction in the treatment of children with CVA can be effectively reduced serum levels of inflammatory factors,promote remission of clinical symptoms,and improve the clinical efficacy.
出处
《陕西中医》
2017年第10期1358-1360,共3页
Shaanxi Journal of Traditional Chinese Medicine
关键词
哮喘/中西医结合疗法
射干麻黄汤
孟鲁司特钠
炎症因子
Asthma /integrated Chinese traditional and western medicine therapy Shegan Mahuang decoc-tion Montelukast Inflammatory factors
