摘要
目的 :观察中药降脂方对红细胞膜胆固醇与磷脂比值 (Ch/ Pl)变化。方法 :用高脂饲料造成家兔实验性高血脂症模型 ,酶法测定胆固醇 (Ch) ,用分光光度法测定磷脂 (Pl)。实验设空白对照组、模型组、中药组和多烯康组。分别观察中药降脂方的降脂作用和对红细胞膜成分的影响。结果 :中药降脂方对高脂血症家兔有较好的降脂作用 ,红细胞膜 Ch/ Pl也有所下降。结论 :这项指标的建立对于临床高血脂、高血压。
Objective: To investigate the effect of Lowering lipid recipe composed of several Chinese herbs on elements in the erythrocyte membrane. Methods: The experimental hyperlipidemia of rabbits was induced by means of feeding stuff containing high lipid; the erythrocyte membrane was prepared with freezing centrifugation; phosphatide(PI) and cholesterol were determined with colorimetric method and enzyme method respectively.The animals were grouped into control group, model group and two drug administration groups. Results: Lowering Lipid Recipe cut down lipid of rabbit with Hyperlipidmia, correspondingly Ch/Pl in the erythrocyte membrane was decreased. The results prompt that the establishment of this reference index is valuable for clinical diagnosis of hypertension, coronary heart disease and so on.
出处
《天津药学》
2002年第4期28-30,共3页
Tianjin Pharmacy
关键词
高脂血症
中药降脂方
红细胞膜磷脂
红细胞膜胆固醇
Lowering lipid recipe composed of chinese herbs,erythrocyte membrane phosphatide cholesterol
