摘要
目的:观察逍遥散加减联合西药治疗月经不调肝郁气滞证的临床疗效。方法:选取112例月经不调肝郁气滞证患者为研究对象,随机分为观察组与对照组,每组56例。观察组采用逍遥散加减联合西药治疗,对照组单纯使用西药治疗。治疗3个月经周期后评估临床疗效,观察治疗前后患者血清雌二醇(E_2)、卵泡刺激素(FSH)、黄体生成素(LH)水平,记录用药期间发生的不良反应。结果:观察组总有效率89.29%,对照组总有效率71.43%,2组比较,差异有统计学意义(P<0.05)。治疗后,2组E_2水平均较治疗前升高(P<0.05),FSH及LH水平均较治疗前降低(P<0.05);观察组的E_2水平比对照组升高更明显(P<0.05);2组FSH及LH水平比较,差异均无统计学意义(P>0.05)。观察组药物不良反应发生率5.36%(3/56),对照组药物不良反应发生率3.57%(2/56),2组比较,差异无统计学意义(P>0.05)。结论:逍遥散加减联合西药治疗能有效改善月经不调肝郁气滞证患者的临床症状,调节性激素水平,药物不良反应少。
Objective： To observe the clinical effect of modified Xiaoyao San combined with western medicine for menoxenia of liver and qistagnation type. Methods：Selected 112 cases of patients with menoxenia of liver and qistagnation type in our hospital as study objects,and divided theminto the observation group and the control group randomly,56 cases in each group. The observation group was treated with modified Xiaoyao San combined with western medicine,while the control group was only treated with western medicine. After three menstrual cycles,evaluated the clinical effect,observed levels of estrogen（E2）, follicle stimulating hormone（FSH） and luteinizing hormone（LH） before and after treatment in both groups,and recorded adverse reaction during the treatment. Results：The total effective rate was 89.29% in the observation group and 71.43% in the control group, the difference being significant（P 0.05）. After treatment, comparing with those before treatment, E2 levels in both groups were increased（P 0.05）, while levels of FSHand LHin both groups were decreased（P0.05）. E2 levels in the observation group were risen more obviously than those in the control group（P0.05）.Compared levels of FSHand LHbetween the two groups,there was no significance being found in the difference（P0.05）.The incidence of adverse reaction was 5.36% in the observation group（3/56） and 3.57% in the control group（2/56）,there being no significance in the difference（P0.05）. Conclusion：The therapy of modified Xiaoyao San combined with western medicine can effectively improve the clinical symptoms of patients with menoxenia of liver and qistagnation type. The therapy can also regulate sex hormone level and cause little adverse reaction.
出处
《新中医》
CAS
2017年第10期91-93,共3页
New Chinese Medicine
关键词
月经不调
肝郁气滞证
中西医结合疗法
逍遥散
性激素
Menoxenia
Liver and qi stagnation type
Integrated Chinese and western medicine therapy
Xiaoyao San
Sex hormone
