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从肠道菌群探讨肥胖从脾论治的机理 被引量:20

Discussion on the Mechanism of Obesity Treatment from Spleen By Intestinal Microflora
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摘要 肥胖已成为严重威胁人类健康的疾病之一,其发病是遗传、环境因素及生活方式相互作用的结果。大量研究表明,肠道菌群在肥胖的发生发展过程中起着重要的作用,其机制主要涉及促进能量吸收、激活炎症反应、调节肠道通透性等多个方面,因此调节肠道菌群可以有效改善肥胖。中医认为肥胖的根本在于脾胃功能失调,临床从脾论治行之有效。脾主运化水谷,肠道菌群影响消化吸收,二者生理功能相似,肠道菌群的研究为中医从脾论治肥胖提供了新思路,故从肠道菌群入手阐述中医从脾论治肥胖的机理。 Obesity has become one of the serious diseases that threaten human health,and its incidence is the result of genetic,environmental and lifestyle factors. A large number of studies show that intestinal flora plays an important role in the occurrence and development of obesity,its mechanism mainly involves many aspects,such as promoting energy absorption,activating the inflammatory response,regulating intes tinal permeability,regulating the intestinal flora can effectively improve obesity. Traditional Chinese Medicine believes that the disorder of spleen and stomach is the pathogenesis of obesity,dealing with the spleen is an effective treatment of obesity. The spleen governs the water trough,the intestinal flora affects the digestion and absorption,so the two physiological functions are similar. The research of the intestinal flora provides a new idea for the treatment of obesity. Therefore,this article takes the intestinal flora as the breakthrough point,expounds the mechanism of TCM from the spleen on the treatment of obesity.
出处 《中国中医基础医学杂志》 CSCD 北大核心 2017年第9期1214-1216,共3页 JOURNAL OF BASIC CHINESE MEDICINE
关键词 脾胃论 肥胖 肠道菌群 Theory of the spleen and stomach Obesity Intestinal flora
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