摘要
磁性液体是一种液态的磁性材料,在交变磁场作用下可以吸收磁场能量转化为热量,具有良好的生物相容性,非常适合作为肿瘤热疗的热介质。根据磁性液体的磁热效应,设计了实验用C型线圈,并仿真计算了线圈磁场的大小和均匀性;建立了磁性液体肿瘤热疗的三维仿真模型,分析了磁性液体注入量和注入点数对肿瘤组织中温度场的影响,仿真结果说明肿瘤组织的温度随磁性液特体注入量和注入点数的增加而增加;搭建磁性液体肿瘤热疗的离体生物组织实验装置,得到生物组织内部的升温曲线,实验结果与仿真结果吻合性较好。
Magnetic liquid is a kind of liquid magnetic material and can absorb magnetic field energy into heat in the alternating magnetic field. Magnetic liquid has good biocompatibility as the thermal medium for tumor treatment. Based on the magnetocaloric effect, the coil for experiment was designed, and the uniformity and intensity of the magnetic field was simulated. A three-dimensional simulation model of magnetic liquid tumor hyperthermia was established. The effects of injection volume and injection points of magnetic liquid on the temperature field in tumor tissue were studied. The simulated results show that the temperature of the tumor tissue increases with the injection volume and the injection points of the magnetic liquid. Finally, the experimental device for biological tissue was built. The temperature data the biological tissue are measured. The experimental results are in good agreement with the simulation results.
出处
《功能材料》
EI
CAS
CSCD
北大核心
2017年第10期10089-10093,共5页
Journal of Functional Materials
基金
河北省自然科学基金资助项目(E2015202241)
关键词
磁性液体
磁热效应
交变磁场
肿瘤热疗
magnetic liquid
magnetocaloric effect
alternating magnetic field
tumor hyperthermia
