摘要
目的探讨超声造影联合弹性成像诊断甲状腺癌的价值。方法收集2014年3月至2015年12月经筛查的139例患者的168个甲状腺结节。根据检查方法分为:超声造影组52例患者共66个结节,弹性成像组56例患者共68个结节,超声造影和弹性成像联合组31例患者共34个结节,所有结节均行细针穿刺病理活检。分析结节的病理、常规彩超检查结果及各组的影像学表现情况,采用受试者工作特征曲线(ROC)分析各组在诊断甲状腺癌中的效能。结果 168个甲状腺结节均经病理组织学证实,其中良性112个,恶性56个。超声造影组良性41个,恶性25个;弹性成像组良性47个,恶性21个;联合组良性24个,恶性10个。超声造影联合弹性成像、弹性成像及超声造影诊断甲状腺结节良恶性的ROC曲线下面积分别为0.924、0.883、0.847;其灵敏性、特异性、准确性分别为70.0%、75.0%、73.0%,96.8%、94.4%、94.6%和90.0%、77.7%、80.0%。超声造影联合弹性成像的诊断效能优于弹性成像及超声造影单独使用。结论超声造影联合弹性成像技术可大大提高甲状腺癌的诊断率,在临床上有较高的应用价值。
Objective To explore the clinical value of contract enhanced ultrasound （CEUS） and elastography in the diagno- sis of thyroid carcinoma. Methods From March 2014 to December 2015, 168 lesions of 139 patients with thyroid nodes were enrolled and divided into three groups according to the testing means. There were CEUS group of 52 patients with 66 thyroid nodes, elastography group of 56 patients with 68 thyroid nodes and CEUS combine with elastography group of 31 patients with 34 thyroid nodes. All thyroid node lesions were confirmed via needle aspiration biopsy. The pathology, routine color Doppler ultrasound findings and imaging findings of each group were analyzed, and the efficacy of each group in the diagnosis of thyroid cancer was analyzed by receiver operating char- acteristic curve （ROC）. Results One hundred and sixty-eight thyroid nodes （including 109 benign and 59 malignant lesions） of 139 patients were confirmed by pathology. In CEUS group, 41 benign and 25 malignant thyroid nodes were diagnosed. In elastography group, 47 benign and 21 malignant thyroid nodes were diagnosed. In CEUS combine with elastography group, 24 benign and 10 malig- nant thyroid nodes were diagnosed. The ROC curve area of benign and malignant thyroid nodes by the CEUS combine with elastography groups, elastography, CEUS diagnosed were 0. 924, 0. 883, 0. 847 respectively. The sensitivity, specificity and accuracy by the CEUS combine with elastography groups, elastography, CEUS diagnosed were 70. 0%, 75.0%, 73.0%; 96. 8%, 94.4%, 94. 6% and 90. 0%, 77. 7%, 80. 0%. The diagnostic efficacy of CEUS combined with elastography is superior to that of elastography and CEUS a- lone. Conclusion CEUS combine with elastography can obviously improve the diagnosis accuracy of thyroid carcinoma. It has good clinical value in clinic.
出处
《临床肿瘤学杂志》
CAS
2017年第9期823-826,共4页
Chinese Clinical Oncology
关键词
甲状腺癌
超声造影
弹性成像
Thyroid carcinoma
Contrast-enhanced ultrasound （CEUS）
Elastography
